白细胞介素-23/辅助性T细胞17轴与银屑病

被引：7

作者：

余峰

机构：

[1] 杭州市萧山区第三人民医院皮肤科

来源：

浙江中西医结合杂志 | 2016年 / 26卷 / 04期

关键词：

银屑病; 白介素-23; 辅助性T细胞17;

D O I：

暂无

中图分类号：

R758.63 [牛皮癣（银屑病）];

学科分类号：

100227 [皮肤病学];

摘要：

<正>银屑病是一种慢性炎症性皮肤病。过去认为银屑病的发病主要是因为角质形成细胞增生和分化异常所致,而环孢霉素A对银屑病的成功治疗提示了免疫系统在其发病机制中的潜在作用[1]。对银屑病发病及进展过程中相关的细胞及细胞因子的研究发现,辅助性T细胞1（Th1）细胞因子干扰素-γ（IFN-γ）、肿瘤坏死因子-α（TNF-α）及白细胞介素-12（IL-12）而非Th2细胞因子IL-4、IL-5或IL-10的mRNA

引用

页码：402 / 405

页数：4

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