噬菌体展示技术发展

被引:4
作者
罗扬拓 [1 ]
朱承睿 [1 ]
武元 [1 ]
李骢 [2 ]
机构
[1] 中国医科大学
[2] 大连医科大学基础医学院
关键词
噬菌体展示技术; 原理; 应用;
D O I
10.13241/j.cnki.pmb.2011.12.001
中图分类号
Q782 [基因载体];
学科分类号
摘要
噬菌体表面展示技术是一种将外源蛋白或抗体可变区与噬菌体表面特定蛋白质融合并展示于其表面,构建蛋白质或抗体库,并从中筛选特异蛋白质或抗体的基因工程技术。随着该项技术的不断完善和发展,噬菌体展示技术已被广泛应用于生命科学研究的不同领域,并显示了良好的应用前景。
引用
收藏
页码:2389 / 2390+2349 +2349
页数:3
相关论文
共 26 条
[11]  
Energy landscape of a selective tumor homing pentapep tide. Zanuy D,Flores Ortega A,Casanovas J, et al. Journal of Physical Chemistry B . 2008
[12]  
Stamped microbattery electrodesbased on self-assembled M13 viruses. Nam KT,Wartena R,Yoo PJ,et al. Proceedings of the National Academy of Sciences of the United States of America . 2008
[13]  
Directed Assembly of PEGylated-Peptide Coatings for Infection-Resistant Titanium Metal. X.J. Khoo,P. Hamilton,G.A. O’Toole,B.D. Snyder,D.J. Kenan. Journal of the American Chemical Society . 2009
[14]  
A rapid andefficient strategy to generate antigen-specific human monoclonalantibody by in vitro immunization and the phage display method. Matsumoto S E,Yamashita M,Katakure Y,et al. Journal of Immunological Methods . 2008
[15]  
Phage as a molecular recognition element in biosensors immobilized by physical adsorption. Viswaprakash Nanduri,Iryna B. Sorokulova,Alexandre M. Samoylov. Biosensors and Bioelectronics . 2007
[16]  
On t he influence of vector design onantibody phage display. Soltes G,Hust M,Bansal A. Journal of Biotechnology . 2007
[17]  
Guanidine alkaloid analogs asinhibitors of HIV-1 Nef interactions with p53,actin,and p56lck. Olszewski A,Sato K,Aron ZD,et al. Proceedings of the National Academy of Sciences of the United States of America . 2004
[18]  
Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy. FERRARA N,HILLAN K J,NOVOTNY W. Biochemical and Biophysical Research Communications . 2005
[19]  
The origin of phage virology. Pennazio S. Riv Biol . 2006
[20]  
Eli minating helper phagefromphage display〔J〕. L Chasteen,J Ayriss,P Pavlik,et al. Nucleic Acids Research . 2006