淫羊藿苷治疗骨质疏松的研究进展

被引:26
作者
刘广飞
程才
王璐
韩红敏
李勇
机构
[1] 沧州市中心医院骨一科河北医科大学教学医院
关键词
淫羊藿苷; 骨质疏松; 研究进展;
D O I
10.13241/j.cnki.pmb.2015.26.047
中图分类号
R259 [现代医学内科疾病];
学科分类号
100201 [内科学];
摘要
淫羊藿是中医常用的治疗骨质疏松的药物,其主要有效成分是多糖和黄酮类化合物具有补肾壮阳、祛风除湿、强筋健骨等功效。近年来研究表明,淫羊藿苷不仅可以促进骨髓间充质干细胞和成骨细胞的骨形成活性,而且能够抑制破骨细胞的分化成熟,具有较强的抗骨质疏松活性。本文从骨髓间充质干细胞、成骨细胞、破骨细胞及其代谢物雌激素样作用等方面综述淫羊藿苷治疗骨质疏松的研究进展,为后续研究与临床应用奠定基础。
引用
收藏
页码:5185 / 5188
页数:4
相关论文
共 16 条
[1]
Local administration of icariin contributes to peripheral nerve regeneration and functional recovery.[J].Bo Chen;Su-ping Niu;Zhi-yong Wang;Zhen-wei Wang;Jiu-xu Deng;Pei-xun Zhang;Xiao-feng Yin;Na Han;Yu-hui Kou;Bao-guo Jiang;.Neural Regeneration Research.2015, 01
[2]
Yizhijiannao Granule and a combination of its effective monomers;icariin and Panax notoginseng saponins;inhibit early PC12 cell apoptosis induced by beta-amyloid(25-35).[J]..Neural Regeneration Research.2012, 24
[3]
Icariin upregulates phosphorylated cyclic adenosine monophosphate response element binding protein levels in the hippocampus of the senescence-accelerated mouse.[J]..Neural Regeneration Research.2012, 12
[4]
Icariin Prevents Amyloid Beta-Induced Apoptosis via the PI3K/Akt Pathway in PC-12 Cells.[J].Dongdong Zhang;Zhe Wang;Chenxia Sheng;Weijun Peng;Shan Hui;Wei Gong;Shuai Chen;Ki-Wan Oh.Evidence-Based Complementary and Alternative Medicine.2015,
[5]
Retracted: Immunization Coverage: Role of Sociodemographic Variables.[J].Advances in Preventive Medicine.Advances in Preventive Medicine.2014,
[6]
Clinician's Guide to Prevention and Treatment of Osteoporosis [J].
Cosman, F. ;
de Beur, S. J. ;
LeBoff, M. S. ;
Lewiecki, E. M. ;
Tanner, B. ;
Randall, S. ;
Lindsay, R. .
OSTEOPOROSIS INTERNATIONAL, 2014, 25 (10) :2359-2381
[7]
Osteoporosis in the European Union: medical management, epidemiology and economic burden [J].
Hernlund, E. ;
Svedbom, A. ;
Ivergard, M. ;
Compston, J. ;
Cooper, C. ;
Stenmark, J. ;
McCloskey, E. V. ;
Jonsson, B. ;
Kanis, J. A. .
ARCHIVES OF OSTEOPOROSIS, 2013, 8 (1-2)
[8]
Osteoporosis in the European Union: a compendium of country-specific reports [J].
Svedbom, A. ;
Hernlund, E. ;
Ivergard, M. ;
Compston, J. ;
Cooper, C. ;
Stenmark, J. ;
McCloskey, E. V. ;
Jonsson, B. ;
Kanis, J. A. .
ARCHIVES OF OSTEOPOROSIS, 2013, 8 (1-2)
[9]
SCOPE: a scorecard for osteoporosis in Europe [J].
Kanis, J. A. ;
Borgstrom, F. ;
Compston, J. ;
Dreinhoefer, K. ;
Nolte, E. ;
Jonsson, L. ;
Lems, W. F. ;
McCloskey, E. V. ;
Rizzoli, R. ;
Stenmark, J. .
ARCHIVES OF OSTEOPOROSIS, 2013, 8 (1-2)
[10]
Epimedium Extract Promotes Peripheral Nerve Regeneration in Rats.[J].Yuhui Kou;Zhiyong Wang;Zhihong Wu;Peixun Zhang;Yu Zhang;Xiaofeng Yin;Xisheng Wong;Guixing Qiu;Baoguo Jiang;Bashar Saad.Evidence-Based Complementary and Alternative Medicine.2013,