α-突触核蛋白在神经细胞损害中的作用

被引：3

作者：

李凡

杨永强

张越

马书玲

机构：

[1] 河南科技大学法医学院

来源：

医学综述 | 2013年 / 19卷 / 11期

关键词：

α-突触核蛋白; 神经细胞损害; 神经变性疾病; 脑损伤; 酒精和毒品依赖与成瘾;

D O I：

暂无

中图分类号：

R741.02 [神经病理学、病因学];

学科分类号：

100204 [神经病学];

摘要：

α-突触核蛋白(α-syn)在脊椎动物脑组织中广泛表达,与神经变性疾病、脑损伤、酒精和毒品依赖以及成瘾神经细胞损害等关系密切。对α-syn的基因定位、结构特点、表达与分布、生理功能、毒性作用、异常聚集及其与神经变性疾病、脑损伤、酒精和毒品依赖与成瘾神经细胞损害的关系进行总结分析,有利于阐明神经细胞变性疾病、脑损伤以及酒精和毒品依赖与成瘾神经细胞损害的发生、发展机制,并为医疗干预提供理论基础。

引用

收藏

页码：1931 / 1934

页数：4

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