ERK1/2研究进展及其与神经胶质瘤相关性

被引：28

作者：

潘伟东

王东军

机构：

[1] 广东医学院

来源：

海南医学 | 2011年 / 22卷 / 22期

关键词：

细胞外信号调节激酶; 神经胶质瘤; 增值与侵袭; 凋亡;

D O I：

暂无

中图分类号：

R739.4 [神经系肿瘤];

学科分类号：

100115 [医学神经生物学];

摘要：

细胞外信号调节激酶(Extracellular signal-regulated kinase,ERK)是有丝分裂原活化蛋白激酶(Mitogen-activated protein kinases,MAPKs)家族的一个重要亚族。ERK的功能是控制细胞分化,ERK的活化被认为与细胞的增殖、分化、迁移、侵袭、凋亡、癌性转化等密切相关。研究并利用ERK1/2在神经胶质瘤形成中的作用能更好的指导神经胶质瘤治疗策略的制定,本文就近年来ERK1/2研究进展及与神经胶质瘤相关性予以综述。

引用

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页码：121 / 124

页数：4

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