急性肾损伤早期诊断的生物标志物

被引：14

作者：

付燕 ^{[1
]}

赵斌 ^{[1
]}

机构：

[1] 北京积水潭医院急诊科

来源：

中国危重病急救医学 | 2012年 / 09期

关键词：

肾损伤; 急性; 早期诊断; 生物学标志物;

D O I：

暂无

中图分类号：

R692 [肾疾病];

学科分类号：

1002 ; 100210 ;

摘要：

急性肾损伤（AKI）是临床常见病及多发病,其发病急,病死率高,是导致患者死亡的独立危险因素。临床上常常通过检测血肌酐（SCr）计算肾小球滤过率（GFR）来评价肾功能,但由于GFR下降至75 ml·min·-11.73m-2时SCr才开始升高,下降至正常的50%以下时,SCr才明显上升,且受体内肌肉总量、蛋白摄入量和体内代谢水平等影响,与GFR相关性较差,不能及时、准确地反映出肾功能状况,从而导致患者不能得到及时的治疗,

引用

共 38 条

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