急性肾损伤早期诊断的生物标志物

被引:14
作者
付燕 [1 ]
赵斌 [1 ]
机构
[1] 北京积水潭医院急诊科
关键词
肾损伤; 急性; 早期诊断; 生物学标志物;
D O I
暂无
中图分类号
R692 [肾疾病];
学科分类号
1002 ; 100210 ;
摘要
急性肾损伤(AKI)是临床常见病及多发病,其发病急,病死率高,是导致患者死亡的独立危险因素。临床上常常通过检测血肌酐(SCr)计算肾小球滤过率(GFR)来评价肾功能,但由于GFR下降至75 ml·min·-11.73m-2时SCr才开始升高,下降至正常的50%以下时,SCr才明显上升,且受体内肌肉总量、蛋白摄入量和体内代谢水平等影响,与GFR相关性较差,不能及时、准确地反映出肾功能状况,从而导致患者不能得到及时的治疗,
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