对氧磷酶与肝病关系研究的进展

被引:6
作者
王继贵
机构
[1] 中南大学湘雅二医院检验科
关键词
D O I
暂无
中图分类号
R575 [肝及胆疾病];
学科分类号
100201 [内科学];
摘要
<正>Mazur在1946年首先报告在动物组织中存在一种酶,它能水解有机磷化合物。随后在五十年代早期证明人血清中亦含有此酶,因它能水解有机磷酸盐基质对氧磷(paraoxon),便称之为对氧磷酶(paraoxonase,PON)该酶国际酶学委员会编号为EC3.1.8.1。PON对氧化应激起着重要的抗氧化剂作用,
引用
收藏
页码:335 / 337
页数:3
相关论文
共 6 条
[1]
Serum arylesterase and paraoxonase activity in patients with chronic hepatitis [J].
Kilic, Suleyman Sirri ;
Aydin, Suleyman ;
Kilic, Nermin ;
Erman, Fazilet ;
Aydin, Suna ;
Celik, Ilhami .
WORLD JOURNAL OF GASTROENTEROLOGY, 2005, 11 (46) :7351-7354
[2]
Current status and prospects of studies on human genetic alleles associated with hepatitis B virus infection [J].
Wang, FS .
WORLD JOURNAL OF GASTROENTEROLOGY, 2003, 9 (04) :641-644
[3]
The importance of paraoxonase 1 activity, nitric oxide and lipid peroxidation in hepatosteatosis [J].
Atamer, A. ;
Bilici, A. ;
Yenice, N. ;
Selek, S. ;
Ilhan, N. ;
Atamer, Y. .
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2008, 36 (04) :771-776
[4]
Paraoxonase activity in high-density lipoproteins: A comparison between healthy and obese females [J].
Ferretti, G ;
Bacchetti, T ;
Moroni, C ;
Savino, S ;
Liuzzi, A ;
Balzola, F ;
Bicchiega, V .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2005, 90 (03) :1728-1733
[5]
Non-alcoholic fatty liver disease [J].
Alba, LM ;
Lindor, K .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2003, 17 (08) :977-986
[6]
Proinflammatory cytokines but not acute phase serum amyloid A or C-reactive protein, downregulate paraoxonase 1 (PON1) expression by HepG2 cells [J].
Kumon, Y ;
Nakauchi, Y ;
Suehiro, T ;
Shiinoki, T ;
Tanimoto, N ;
Inoue, M ;
Nakamura, T ;
Hashimoto, K ;
Sipe, JD .
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2002, 9 (03) :160-164