肠易激综合征与应激关系的研究进展

被引:13
作者
田诗雨
吴子刚
机构
[1] 北京大学深圳医院消化科
关键词
肠易激综合征; 应激; 脑肠轴; 肠道菌群;
D O I
暂无
中图分类号
R574 [肠疾病];
学科分类号
100201 [内科学];
摘要
肠易激综合征(IBS)是常见的功能性肠道疾病,其发病机制复杂,与应激关系十分密切。其中,脑肠轴对应激反应的不同环节失调,以及应激所致免疫激活和持续是IBS已得研究确证的重要病理机制。近年来肠道菌群和应激的相互作用对IBS的影响也得到重视。IBS与应激关系的研究进展对IBS的诊断与治疗提供了有益的提示。
引用
收藏
页码:121 / 123
页数:3
相关论文
共 13 条
[1]
Altered neuro-endocrine–immune pathways in the irritable bowel syndrome: the top-down and the bottom-up model [J].
Cristina Stasi ;
Massimo Rosselli ;
Massimo Bellini ;
Giacomo Laffi ;
Stefano Milani .
Journal of Gastroenterology, 2012, 47 :1177-1185
[2]
Novel insights in the role of peripheral corticotropin-releasing factor and mast cells in stress-induced visceral hypersensitivity [J].
Larauche, M. .
NEUROGASTROENTEROLOGY AND MOTILITY, 2012, 24 (03) :201-205
[3]
Gut memories: Towards a cognitive neurobiology of irritable bowel syndrome.[J].Paul J. Kennedy;Gerard Clarke;Eamonn M.M. Quigley;John A. Groeger;Timothy G. Dinan;John F. Cryan.Neuroscience and Biobehavioral Reviews.2011, 1
[4]
Do interactions between stress and immune responses lead to symptom exacerbations in irritable bowel syndrome? [J].
O'Malley, Dervla ;
Quigley, Eamonn M. M. ;
Dinan, Timothy G. ;
Cryan, John F. .
BRAIN BEHAVIOR AND IMMUNITY, 2011, 25 (07) :1333-1341
[5]
Abdominal pain in Irritable Bowel Syndrome: A review of putative psychological; neural and neuro-immune mechanisms.[J].Sigrid Elsenbruch.Brain Behavior and Immunity.2010, 3
[6]
Dysfunctional Cognitions, Anxiety and Depression in Irritable Bowel Syndrome [J].
Thijssen, Annemieke Y. ;
Jonkers, Dorothea M. A. E. ;
Leue, Carsten ;
van der Veek, Patrick P. J. ;
Vidakovic-Vukic, Michelle ;
van Rood, Yanda R. ;
Clemens, Cornelis H. M. ;
Masclee, Ad A. M. .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 2010, 44 (10) :E236-E241
[7]
The burden of IBS: Looking at metrics [J].
Spiegel B.M.R. .
Current Gastroenterology Reports, 2009, 11 (4) :265-269
[8]
Irritable bowel syndrome: towards biomarker identification [J].
Clarke, Gerard ;
Quigley, Eamonn M. M. ;
Cryan, John F. ;
Dinan, Timothy G. .
TRENDS IN MOLECULAR MEDICINE, 2009, 15 (10) :478-489
[9]
Childhood Trauma Is Associated With Hypothalamic-Pituitary-Adrenal Axis Responsiveness in Irritable Bowel Syndrome [J].
Videlock, Elizabeth J. ;
Adeyemo, Mopelola ;
Licudine, Arlene ;
Hirano, Miyoshi ;
Ohning, Gordon ;
Mayer, Minou ;
Mayer, Emeran A. ;
Chang, Lin .
GASTROENTEROLOGY, 2009, 137 (06) :1954-1962
[10]
Stress-related modulation of inflammation in experimental models of bowel disease and post-infectious irritable bowel syndrome: Role of corticotropin-releasing factor receptors.[J].Cornelia Kiank;Yvette Taché;Muriel Larauche.Brain Behavior and Immunity.2009, 1