猪生殖-呼吸综合征病毒蛋白的结构与功能

被引：8

作者：

仇华吉

周彦君

童光志

机构：

[1] 中国农业科学院哈尔滨兽医研究所生物技术国家重点实验室!哈尔滨

来源：

动物医学进展 | 2000年 / 02期

关键词：

猪生殖-呼吸道综合征病毒; 病毒蛋白; 结构; 功能;

D O I：

10.16437/j.cnki.1007-5038.2000.02.006

中图分类号：

Q51 [蛋白质];

学科分类号：

071010 ; 081704 ;

摘要：

猪生殖 -呼吸道综合征 ( PRRS)病毒是新发现的 RNA病毒。其基因组有 8个开放阅读框架 ( ORF) ,ORF1编码病毒的RNA聚合酶 ,ORF2～ 7分别编码糖蛋白GP2～ 5、M蛋白和 N蛋白。本文概括了近几年来国际上对其病毒蛋白的研究成果 ,对这些病毒蛋白的结构、功能及其免疫学地位进行了分析和讨论

引用

页码：23 / 26

页数：4

共 10 条

[1] 猪生殖-呼吸道综合征病毒(PRRSV)CH-la株N基因的分子克隆、序列测定及其比较分析 [J].

仇华吉 ;

童光志 ;

郭宝清 ;

王柳 ;

张绍杰 ;

王玫 ;

于力 ;

刘宝全 .

中国畜禽传染病, 1998, (04) :26-29

[2] A nonstructural and antigenic glycoprotein is encoded by ORF3 of the IAF-Klop strain of porcine reproductive and respiratory syndrome virus [J].

Gonin, P ;

Mardassi, H ;

Gagnon, CA ;

Massie, B ;

Dea, S .

ARCHIVES OF VIROLOGY, 1998, 143 (10) :1927-1940

[3]

Baculovirus Expression of Proteins of Porcine Reproductive and Respiratory Syndrome Virus Strain Olot/91. Involvement of ORF3 and ORF5 Proteins in Protection[J] . Alicia Urniza,Isabel Climent,Juan Plana Duran,Elena Corte′s,Javier Sarraseca,J. Ignacio Casal,Carmen Vela.Virus Genes . 1997 (1)

[4]

Kinetics of humoral immune response to the major structural proteins of the porcine reproductive and respiratory syndrome virus[J] . H. D. Loemba,S. Mounir,H. Mardassi,D. Archambault,S. Dea.Archives of Virology . 1996 (3)

[5]

Molecular analysis of the ORFs 3 to 7 of porcine reproductive and respiratory syndrome virus, Québec reference strain[J] . H. Mardassi,S. Mounir,S. Dea.Archives of Virology . 1995 (8)

[6] COMPARISON OF THE STRUCTURAL PROTEIN-CODING SEQUENCES OF THE VR-2332 AND LELYSTAD VIRUS-STRAINS OF THE PRRS VIRUS [J].

MURTAUGH, MP ;

ELAM, MR ;

KAKACH, LT .

ARCHIVES OF VIROLOGY, 1995, 140 (08) :1451-1460

[7]

Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe[J] . X. -J. Meng,P. S. Paul,P. G. Halbur,M. A. Lum.Archives of Virology . 1995 (4)

[8]

An indirect ELISA for the detection of antiboldies against porcine reproductive and respiratory syndrome virus using recombinant nucleocapsid protein as antigen .2 Denac H,Moser C,Tratschin J D,et al. J Virol Methods . 1997

[9]

Serum immune responses to the proteins of porcine reproductive and respiratory syndrome ( PRRS )virus .2 Nelson E A,Christopher-Hennings J,Benfield D A. J Vet Diagn Invest . 1994

[10]

Seroneutralization of porcine reproductive and respiratory syndrome virus correlates with antibody response to the GP5 major envelope glycoprotein .2 Gonin P,Pirzadeh B,Gagon C A,et al. J Vet Diagn Invest . 1999

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