Toll样受体在支气管哮喘和其他过敏性疾病中的作用

被引:15
作者
祁聪聪
刘春涛
机构
[1] 四川大学华西医院呼吸内科
关键词
Toll样受体; 过敏原; 哮喘; 过敏性鼻炎;
D O I
暂无
中图分类号
R562.25 [];
学科分类号
摘要
Toll样受体识别相应的抗原,启动细胞内信号通路,诱导相应细胞因子的表达,从而影响过敏性疾病的发生发展,而且不同的Toll样受体作用不同,Toll样受体目前已成为过敏性疾病研究的一个热点。本文就对Toll样受体的作用作一综述。
引用
收藏
页码:212 / 217
页数:6
相关论文
共 11 条
[1]
屋尘螨诱导气道上皮TLR4表达和影响T淋巴细胞分化在哮喘气道炎症中的作用 [J].
李鸿佳 ;
周明香 ;
孙文青 ;
王维瑄 ;
王庆 ;
郭鹏 ;
刘春利 ;
曹晓青 ;
陈海荣 ;
李冲 ;
吴金香 ;
董亮 .
中国呼吸与危重监护杂志, 2011, 10 (01) :16-20
[2]
Science Letters:A synthetic Toll-like receptor 2 ligand decreases allergic immune responses in a mouse rhinitis model sensitized to mite allergen [J].
Cheng ZHOU Xiaodong KANG Zhi CHEN Institute of Infectious Diseases the First Affiliated Hospital School of Medicine Zhejiang University Hangzhou China Experimental Animal Center School of Medicine Hangzhou Teachers College Hangzhou China .
Journal of Zhejiang University(Science B:An International Biomedicine & Biotechnology Journal), 2008, (04) :279-285
[3]
脂多糖对大鼠实验性变应性鼻炎的影响 [J].
刘颖 ;
郑春泉 ;
余洪猛 ;
顾瑜蓉 ;
毛涌 ;
丁国强 .
中国实验动物学报, 2007, (04) :289-291+237
[4]
Direct and Indirect Role of Toll-Like Receptors in T Cell Mediated Immunity.[J].Mousa Komai-Koma;.Cellular & Molecular Immunology.2004, 04
[5]
Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma;atopic dermatitis and chronic obstructive pulmonary disease..Hoffjan S;Sternmler S;Parwez Q;Petrasch-Parwez E;Arinir U;Rohde G;Reinitz-Rademacher K;Schultze-Werninghaus G;Bufe A;Epplen JT;.BMC Med Genet.2005, 06
[6]
Endoplasmic reticulum HSP90b1 (gp96;grp94)optimizes B-cell function via chaperoning integrin and TLR but not immunoglobulin..Liu B;Li Z;.Blood.2008,
[7]
Regulatory T cells and Toll-like receptors: What is the missing link? [J].
Dai, Jie ;
Liu, Bei ;
Li, Zihai .
INTERNATIONAL IMMUNOPHARMACOLOGY, 2009, 9 (05) :528-533
[8]
Toll-like receptors on regulatory T cells: expanding immune regulation [J].
Sutmuller, Roger P. M. ;
Morgan, Mary E. ;
Netea, Mihai G. ;
Grauer, Oliver ;
Adema, Gosse J. .
TRENDS IN IMMUNOLOGY, 2006, 27 (08) :387-393
[9]
TLR9-based immunotherapy for allergic disease [J].
Hayashi, Tomoko ;
Raz, Eyal .
AMERICAN JOURNAL OF MEDICINE, 2006, 119 (10) :897.e1-897.e6
[10]
Allergen-independent immunostimulatory sequence oligodeoxynucleotide therapy attenuates experimental allergic rhinitis [J].
Rhee, CS ;
Libet, L ;
Chisholm, D ;
Takabayashi, K ;
Baird, S ;
Bigby, TD ;
Lee, CH ;
Horner, AA ;
Raz, E .
IMMUNOLOGY, 2004, 113 (01) :106-113