巨噬细胞的极化及功能调控

被引：50

作者：

宮甜甜

黄少刚

张玥

李佳

雷蕾

单智焱

机构：

[1] 哈尔滨医科大学组织学与胚胎学教研室

来源：

解剖学报 | 2017年 / 48卷 / 01期

关键词：

巨噬细胞; 极化; 调控;

D O I：

10.16098/j.issn.0529-1356.2017.01.019

中图分类号：

R392 [医学免疫学];

学科分类号：

100108 [医学免疫学];

摘要：

巨噬细胞在体内分布极广,具有高度可塑性,并在机体的发育及内环境的平衡中起到重要作用。应激条件下,巨噬细胞发生极化,极化后的巨噬细胞亚型可以细致调节及回应各种不同的刺激,对炎症反应或疾病的发展及组织器官的修复程度起着关键性的作用,具有重要的临床应用价值。我们在文中概述了巨噬细胞的极化分类,作用机制及不同环境下巨噬细胞的功能转换,为巨噬细胞极化研究提供理论基础。

引用

页码：106 / 110

页数：5

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