与银屑病相关的T辅助细胞研究进展

被引:26
作者
曾亚军
李玲玲
段行武
张润田
陈广山
机构
[1] 北京中医药大学东直门医院
关键词
银屑病; T辅助细胞; 细胞因子; 作用机制;
D O I
暂无
中图分类号
R758.63 [牛皮癣(银屑病)];
学科分类号
100227 [皮肤病学];
摘要
银屑病是一种由多种免疫细胞和细胞因子介导参与的慢性炎症性免疫性疾病。关于银屑病的确切发病机制尚未阐明,研究发现可能与Th1、Th2、Th17、调节性T淋巴细胞(Treg)细胞、Th22细胞及Th9细胞的异常活化并释放大量细胞因子有关。该文围绕这些免疫细胞及其相关细胞因子主要从近年所发现的Th细胞亚群及其相关细胞因子角度综述了近年来与银屑病T辅助细胞的实验研究进展,阐述各个辅助细胞及相关细胞因子在银屑病发病过程中的作用及关联机制,以期能帮助笔者更深入地了解银屑病的发病机制并为今后的实验研究提供依据。
引用
收藏
页码:84 / 87
页数:4
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