DNA修复与人类疾病研究进展

被引:10
作者
孙敬芬
机构
[1] 军事医学科学院放射医学研究所四室北京
关键词
DNA修复; XRCC基因; 人类疾病; 癌症;
D O I
暂无
中图分类号
Q75 [分子遗传学];
学科分类号
071007 ;
摘要
DNA修复是一系列与恢复正常DNA序列结构和维持遗传信息相对稳定有关的细胞反应 ,细胞为了存活而容忍某种类型的DNA损伤或不正常的碱基序列也包括在该定义范围内。DNA修复基因在进化上高度保守[1] 且与许多疾病有关 ,但DNA修复缺陷相关的疾病非常复杂 ,对于DNA修复和这些疾病关系的研究 ,还没见系统的报道 ,本文拟对DNA修复系统缺陷与其诱发疾病的关系进行综述
引用
收藏
页码:261 / 265
页数:5
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