植物多糖对巨噬细胞的免疫调节作用

被引：61

作者：

谢燕霞

安利国

杨桂文

机构：

[1] 山东师范大学生命科学学院

来源：

中国生物化学与分子生物学报 | 2008年 / 04期

关键词：

植物多糖; 免疫调节; 巨噬细胞;

D O I：

10.13865/j.cnki.cjbmb.2008.04.005

中图分类号：

Q946 [植物生物化学];

学科分类号：

071001 [植物学];

摘要：

植物多糖是一类广泛存在于植物中具有多种生物学活性的天然大分子物质,对免疫系统的影响普遍认为是通过对天然免疫系统的调节作用,尤其是对巨噬细胞免疫功能的影响.许多研究表明,植物多糖与巨噬细胞表面多种受体结合启动不同信号途径而发挥生物学作用.本文综述了来源于不同种属的多种植物多糖对巨噬细胞释放活性氧、分泌细胞因子和趋化因子等的免疫调节作用,为新型免疫调节药物的研究开发提供了新的思路.

引用

页码：307 / 314

页数：8

共 20 条

[1]

Chemically-modified polysaccharide extract derived from Leucaena leucocephala alters Raw 264.7 murine macrophage functions [J].

Gamal-Eldeen, Amira M. ;

Amer, Hassan ;

Helmy, Wafaa A. ;

Talaat, Roba M. ;

Ragab, Halla .

INTERNATIONAL IMMUNOPHARMACOLOGY, 2007, 7 (06) :871-878

[2]

Immunomodulating activities of acidic sulphated polysaccharides obtained from the seaweed Ulva rigida C. Agardh [J].

Leiro, Jose M. ;

Castro, Rosario ;

Arranz, Jon A. ;

Lamas, Jesus .

INTERNATIONAL IMMUNOPHARMACOLOGY, 2007, 7 (07) :879-888

[3]

Immunoactive polysaccharide-rich fractions from Panax notoginseng [J].

Zhu, Ying ;

Pettolino, Filomena ;

Mau, Shaio-lim ;

Shen, Yu-Chang ;

Chen, Chie-Fu ;

Kuo, Yuh-Chi ;

Bacic, Antony .

PLANTA MEDICA, 2006, 72 (13) :1193-1199

[4]

Mechanism of macrophage activation by (1,4)-α-D-glucan isolated from Tinospora cordifolia [J].

Nair, P. K. Raveendran ;

Melnick, Steven J. ;

Ramachandran, Reshma ;

Escalon, Enrique ;

Ramachandran, Cheppail .

INTERNATIONAL IMMUNOPHARMACOLOGY, 2006, 6 (12) :1815-1824

[5]

Cancer chemopreventive and anti-inflammatory activities of chemically modified guar gum [J].

Gamal-Eldeen, Amira M. ;

Amer, Hassan ;

Helmy, Wafaa A. .

CHEMICO-BIOLOGICAL INTERACTIONS, 2006, 161 (03) :229-240

[6]

Fucoidan induces nitric oxide production via p38 mitogen-activated protein kinase and NF-κB-dependent signaling pathways through macrophage scavenger receptors [J].

Nakamura, T ;

Suzuki, H ;

Wada, Y ;

Kodama, T ;

Doi, T .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2006, 343 (01) :286-294

[7]

Polysaccharide biological response modifiers [J].

Leung, M. Y. K. ;

Liu, C. ;

Koon, J. C. M. ;

Fung, K. P. .

IMMUNOLOGY LETTERS, 2006, 105 (02) :101-114

[8]

Macrophage immunomodulatory activity of polysaccharides isolated from Juniperus scopolorum.[J].Igor A. Schepetkin;Craig L. Faulkner;Laura K. Nelson-Overton;James A. Wiley;Mark T. Quinn.International Immunopharmacology.2005, 13

[9]

Characterization and immunostimulatory activity of an (1→6)-a-D-glucan from the root of Ipomoea batatas [J].

Zhao, GH ;

Kan, JQ ;

Li, ZX ;

Chen, ZD .

INTERNATIONAL IMMUNOPHARMACOLOGY, 2005, 5 (09) :1436-1445

[10]

Macrophage activation by polysaccharide isolated from Astragalus membranaceus.[J].Kun Yeong Lee;Young Jin Jeon.International Immunopharmacology.2005, 7

← 1 2 →