别嘌醇致药疹伴嗜酸性粒细胞增多及系统症状

被引:1
作者
黄智勇
谢红
机构
[1] 漳州市解放军第一七五医院肾内科
关键词
别嘌醇; 药疹; 嗜酸性粒细胞增多;
D O I
10.15912/j.cnki.gocm.2014.01.199
中图分类号
R758.2 [变态反应性及中毒性皮肤病];
学科分类号
100227 [皮肤病学];
摘要
<正>1病例资料患者女性,65岁,因"全身皮疹、发热1周,尿少1 d"入院。入院前32 d因双膝关节痛就诊当地医院,查肾功能UREA 4.3 mmol/L、CRE 79.2μmol/L、UA 608μmol/L。予"别嘌醇100 mg,3次/日"等处理。入院前1周无明显诱因出现发热,最高40.2℃,同时出现全身皮疹,伴瘙痒,双膝关节轻微疼痛。当地医院对症处理,效果差。入院前1 d出现尿量减少,24 h约500 mL。查体:体温40℃,
引用
收藏
页码:185 / 186
页数:2
相关论文
共 3 条
[1]
Clinical Pharmacogenetics Implementation Consortium Guidelines for Human Leukocyte Antigen-B Genotype and Allopurinol Dosing [J].
Hershfield, M. S. ;
Callaghan, J. T. ;
Tassaneeyakul, W. ;
Mushiroda, T. ;
Thorn, C. F. ;
Klein, T. E. ;
Lee, M. T. M. .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2013, 93 (02) :153-158
[2]
High Dose Allopurinol Reduces Left Ventricular Mass In Patients With Ischemic Heart Disease.[J].Sushma Rekhraj;Stephen J. Gandy;Benjamin R. Szwejkowski;M. Adnan Nadir;Awsan Noman;J. Graeme Houston;Chim C. Lang;Jacob George;Allan D. Struthers.Journal of the American College of Cardiology.2012,
[3]
Association between HLA‐B*58:01 allele and severe cutaneous adverse reactions with allopurinol in Han Chinese in Hong Kong.[J].M.L.S. Chiu;M. Hu;M.H.L. Ng;C.K. Yeung;J.C‐Y. Chan;M.M. Chang;S.H. Cheng;L. Li;B. Tomlinson.British Journal of Dermatology.2012, 1