金丝桃苷药理作用及其作用机制的研究进展

被引：69

作者：

李锦松 ^{[1
]}

陈剑鸿 ^{[2
]}

孟民杰 ^{[1
]}

机构：

[1] 广东药学院生命科学与生物制药学院

[2] 第三军医大学大坪医院大坪野战研究所药学部

来源：

广东药学院学报 | 2015年 / 31卷 / 02期

关键词：

金丝桃苷; 药理作用; 机制; 氧化应激;

D O I：

暂无

中图分类号：

R285.5 [中药实验药理];

学科分类号：

100806 [中药药理学];

摘要：

综述金丝桃苷抗急性肝损伤、抗抑郁、抗炎症、抗血栓、抗癌、抗菌、抗氧化应激和抗细胞凋亡等药理作用,介绍其发挥药理作用的主要机制,为进一步研究金丝桃苷的药理作用、潜在治疗靶点和机制提供理论依据。

引用

页码：269 / 272

页数：4

共 19 条

[1]

金丝桃苷对CCl4诱导大鼠急性肝损伤抗氧化应激研究 [J].

黄明春 ;

陈剑鸿 ;

胡小刚 ;

夏培元 ;

蔡永青 ;

王强 .

局解手术学杂志, 2013, 22 (06) :588-590+593

[2]

Hyperoside Inhibits High-Glucose-Induced Vascular Inflammation In Vitro and In Vivo [J].

Ku, Sae-Kwang ;

Kwak, Soyoung ;

Kwon, O-Jun ;

Bae, Jong-Sup .

INFLAMMATION, 2014, 37 (05) :1389-1400

[3]

Hyperoside Regulates the Level of Thymic Stromal Lymphopoietin through Intracellular Calcium Signalling [J].

Han, Na-Ra ;

Go, Ji-Hyun ;

Kim, Hyung-Min ;

Jeong, Hyun-Ja .

PHYTOTHERAPY RESEARCH, 2014, 28 (07) :1077-1081

[4]

Combination of quercetin and hyperoside has anticancer effects on renal cancer cells through inhibition of oncogenic microRNA-27a [J].

Li, Wei ;

Liu, Min ;

Xu, Yun-Fei ;

Feng, Yuan ;

Che, Jian-Ping ;

Wang, Guang-Chun ;

Zheng, Jun-Hua .

ONCOLOGY REPORTS, 2014, 31 (01) :117-124

[5]

Antiplatelet activities of hyperoside in vitro and in vivo [J].

Ku, Sae-Kwang ;

Yoo, Hayoung ;

Zhou, Wei ;

Na, MinKyun ;

Bae, Jong-Sup .

ANIMAL CELLS AND SYSTEMS, 2014, 18 (03) :204-209

[6]

Regulation of Nrf2—an update.[J].Suryakant K. Niture;Raju Khatri;Anil K. Jaiswal.Free Radical Biology and Medicine.2014,

[7]

The effect of hyperoside on the functional recovery of the ischemic/reperfused isolated rat heart: Potential involvement of the extracellular signal-regulated kinase 1/2 signaling pathway.[J].Zi-lin Li;Jing Hu;Ya-ling Li;Feng Xue;Li Zhang;Jia-qi Xie;Zhen-hua Liu;Hua Li;Ding-hua Yi;Jin-cheng Liu;Si-wang Wang.Free Radical Biology and Medicine.2013,

[8]

Antithrombotic and profibrinolytic activities of isorhamnetin-3- O -galactoside and hyperoside.[J].Sae-Kwang Ku;Tae Hoon Kim;Sangkyu Lee;Seong Min Kim;Jong-Sup Bae.Food and Chemical Toxicology.2013,

[9]

Antidepressant-like effect of hyperoside isolated from Apocynum venetum leaves: Possible cellular mechanisms.[J].Meizhu Zheng;Chunming Liu;Fengguang Pan;Dongfang Shi;Yuchi Zhang.Phytomedicine.2011, 2

[10]

Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation.[J].Brooks M. Hybertson;Bifeng Gao;Swapan K. Bose;Joe M. McCord.Molecular Aspects of Medicine.2011, 4

← 1 2 →