丝组二肽对DNA的切割作用的研究

被引：6

作者：

万荣

王宁

赵玉芬

机构：

[1] 清华大学生命科学与工程研究院化学系教育部生命有机磷化学重点实验室!北京

来源：

高等学校化学学报 | 2001年 / 04期

关键词：

丝组二肽; DNA; 切割; 水解机理;

D O I：

暂无

中图分类号：

O629 [天然化合物];

学科分类号：

摘要：

Linear and supercoiled DNA were cleaved by HPLC purified seryl histidine dipeptide(SH). It was found that the DNA fragments produced by the reaction of SH and DNA could be ligated together by T 4 DNA ligase. This result implied that the SH was the first example of the ion free artificial DNA cleavage agent that could split DNA by hydrolysis mechanism.

引用

页码：598 / 600

页数：3