针刺治疗脑卒中后肢体痉挛的机制研究探讨

被引:43
作者
王俊翔
马良宵
杨洋
宋越
机构
[1] 北京中医药大学针灸推拿学院
关键词
脑卒中; 痉挛; 针刺; 神经递质; 机制研究;
D O I
暂无
中图分类号
R246.6 [神经精神病科];
学科分类号
100225 [精神医学];
摘要
卒中后肢体痉挛是阻碍患者肢体运动功能恢复的主要原因,严重影响了脑卒中患者的身心健康。针刺对卒中后肢体痉挛疗效肯定,但机制尚不完全明确。本文通过梳理针刺对痉挛相关神经递质及受体、运动神经元兴奋性、炎性细胞因子、细胞信号传导相关物质及离子通道的影响,探讨针刺抗痉挛的可能靶点和有效途径,为针刺抗痉挛的机制研究提供方向。
引用
收藏
页码:470 / 475
页数:6
相关论文
共 49 条
[1]
近十年脑卒中后痉挛的中西医临床研究进展 [D]. 
朴雪梅 .
北京中医药大学,
2013
[2]
电针抗脑卒中偏瘫肢体痉挛代谢型谷氨酸受体1(mGluR1)受体机制研究 [D]. 
冯媛 .
成都中医药大学,
2006
[3]
Effect of acupuncture on inflammatory cytokines expression of spastic cerebral palsy rats [J].
Qi, Ya-Chao ;
Xiao, Xiang-Jian ;
Duan, Rui-Sheng ;
Yue, Yue-Hong ;
Zhang, Xiao-Ling ;
Li, Jun-Tao ;
Li, Ya-Zhou .
ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2014, 7 (06) :492-495
[4]
Effect of catgut implantation at acupoints on GABA B and mGluR1 expressions in brain stem of rats with spasticity after stroke.[J].Chengmei Liu;Ruiqing Li;Xiaolei Song;Xiaodong Feng.Journal of Traditional Chinese Medicine.2014, 5
[5]
Electroacupuncture promotes neurological functional recovery via the retinoic acid signaling pathway in rats following cerebral ischemia-reperfusion injury [J].
Hong, Jiangcong ;
Wu, Guangwen ;
Zou, Yulong ;
Tao, Jing ;
Chen, Lidian .
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2013, 31 (01) :225-231
[6]
Compartmentation of GABA metabolism raises intriguing questions.[J].Barry J. Shelp;Robert T. Mullen;Jeffrey C. Waller.Trends in Plant Science.2011, 2
[7]
Altered chloride homeostasis in neurological disorders: a new target.[J].Yves De Koninck.Current Opinion in Pharmacology.2006, 1
[8]
Development of GABA-sensitive spasticity and rigidity in rats after transient spinal cord ischemia: A qualitative and quantitative electrophysiological and histopathological study [J].
Kakinohana, O. ;
Hefferan, M. P. ;
Nakamura, S. ;
Kakinohana, M. ;
Galik, J. ;
Tomori, Z. ;
Marsala, J. ;
Yaksh, T. L. ;
Marsala, M. .
NEUROSCIENCE, 2006, 141 (03) :1569-1583
[9]
Role of GABA in electro-acupuncture therapy on cerebral ischemia induced by occlusion of the middle cerebral artery in rats [J].
Gan, P ;
Cheng, JS ;
Ng, YK ;
Ling, EA .
NEUROSCIENCE LETTERS, 2005, 383 (03) :317-321
[10]
Two developmental switches in GABAergic signalling: the K<sup>+</sup>–Cl<sup>−</sup> cotransporter KCC2 and carbonic anhydrase CAVII.[J].Claudio Rivera;Juha Voipio;Kai Kaila.The Journal of Physiology.2005, 1