肝病患者糖代谢、胰岛素和C肽的研究

被引：7

作者：

胰岛B细胞功能研究协作组

机构：

来源：

中华医学杂志 | 1982年 / 11期

关键词：

D O I：

暂无

中图分类号：

R575 [肝及胆疾病];

学科分类号：

1002 ; 100201 ;

摘要：

对13例急性肝炎,22例慢性肝炎和20例肝硬变患者进行了胰岛B细胞功能和糖代谢的研究。急性和慢性肝炎组平均空腹血糖比正常人为低,而肝硬变组则高于正常。于急性和慢性肝炎组作100g葡萄糖耐量试验时,血糖在60、120分钟的反应值高于正常。肝硬变组糖耐量明显受损,并有空腹高胰岛素血症,三组肝病患者对糖耐量的反应均高于正常人,以慢性肝炎组为甚。三组肝病空腹C肽均正常,但在口服葡萄糖后C肽的反应与胰岛素有明显差别。于急性肝炎和慢性肝炎组,C肽反应不延迟,其反应低于正常人。提示肝病患者高胰岛素血症并非由于胰岛B细胞功能亢进,而是由于病变的肝脏摄取胰岛素减少所致。

引用

共 22 条

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