骨髓间充质干细胞联合干细胞因子治疗炎症性肠病

被引：6

作者：

连丽莹

曲波

金世柱

祝芳

仝甲钊

机构：

[1] 哈尔滨医科大学附属第二医院消化内科

来源：

胃肠病学和肝病学杂志 | 2015年 / 24卷 / 05期

关键词：

炎症性肠病; 干细胞; 骨髓移植; 间充质干细胞; 干细胞因子;

D O I：

暂无

中图分类号：

R574.62 [结肠疾病];

学科分类号：

100201 [内科学];

摘要：

炎症性肠病(inflammatory bowel disease,IBD)是一种可累及全身原因未明的慢性非特异性肠道炎症性疾病,包括溃疡性结肠炎(ulcerative colitis,UC)和克罗恩病(Crohn’s disease,CD),其发病率呈逐年上升趋势,且多为青壮年发病,并发症多。间充质干细胞联合干细胞因子治疗炎症和自身免疫疾病是一个新兴的领域,在不久的将来或许可以为IBD的治疗提供新的机会。本文就间充质干细胞联合干细胞因子治疗IBD作一概述。

引用

页码：612 / 614

页数：3

共 9 条

[1]

Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts.[J].Maya Fakhry;René Buchet;David Magne;Eva Hamade;Bassam Badran;.World Journal of Stem Cells.2013, 04

[2]

Intravenous injection of mesenchymal stem cells is effective in treating liver fibrosis [J].

Zhao, Wei ;

Li, Jun-Jie ;

Cao, Da-Yong ;

Li, Xiao ;

Zhang, Lin-Ying ;

He, Yong ;

Yue, Shu-Qiang ;

Wang, De-Sheng ;

Dou, Ke-Feng .

WORLD JOURNAL OF GASTROENTEROLOGY, 2012, 18 (10) :1048-1058

[3]

骨髓间充质干细胞免疫调节作用的研究进展 [J].

金世柱 ;

韩明子 .

胃肠病学, 2007, (05) :308-310

[4]

亚太地区炎症性肠病处理共识意见(一) [J].

欧阳钦 ;

Rakesh Tandon ;

KL Goh ;

潘国宗 ;

KM Fock ;

Claudio Fiocchi ;

SK Lam ;

萧树东 ;

张虎 ;

梁红亮 ;

王玉芳 .

胃肠病学, 2006, (04) :233-238

[5]

Bone marrow derived mesenchymal stem cell transplantation in cerebellar degeneration: A behavioral study [J].

Edalatmanesh, Mohammad Amin ;

Bahrami, Ahmad Reza ;

Hosseini, Ebrahim ;

Hosseini, Mahmoud ;

Khatamsaz, Saeid .

BEHAVIOURAL BRAIN RESEARCH, 2011, 225 (01) :63-70

[6]

Myocardial Injection With GSK-3β–Overexpressing Bone Marrow–Derived Mesenchymal Stem Cells Attenuates Cardiac Dysfunction After Myocardial Infarction.[J].Jaeyeaon Cho;Peiyong Zhai;Yasuhiro Maejima;Junichi Sadoshima.Circulation Research.2011, 4

[7]

Bone Marrow Mesenchymal Stem Cells [J].

Ohishi, Masanobu ;

Schipani, Ernestina .

JOURNAL OF CELLULAR BIOCHEMISTRY, 2010, 109 (02) :277-282

[8]

Human Mesenchymal Stem Cells Inhibit Neutrophil Apoptosis: A Model for Neutrophil Preservation in the Bone Marrow Niche.[J].LizziaRaffaghello;GiordanoBianchi;MariaBertolotto;FabrizioMontecucco;AlessandroBusca;FrancoDallegri;LucianoOttonello;VitoPistoia.STEM CELLS.2009, 1

[9]

Subcutaneous adipose tissue–derived stem cells facilitate colonic mucosal recovery from 2;4;6‐trinitrobenzene sulfonic acid (TNBS)–induced colitis in rats.[J].YugoAndo;MuneoInaba;YutakuSakaguchi;MasanobuTsuda;Guo KeQuan;MarikoOmae;KazuichiOkazaki;SusumuIkehara.Inflamm Bowel Dis.2008, 6

← 1 →