维生素D代谢及25-羟基维生素D测定方法研究进展

被引：62

作者：

李水军 ^{[1
]}

王思合 ^{[2
]}

周建烈 ^{[1
]}

余琛 ^{[1
]}

机构：

[1] 上海市徐汇区中心医院中心实验室

[2] 美国克利夫兰医学中心病理学与检验医学研究所

来源：

国际检验医学杂志 | 2012年 / 33卷 / 24期

关键词：

25-羟基维生素D; 免疫酶技术; 液相色谱技术; 质谱技术;

D O I：

暂无

中图分类号：

R446.11 [血液学检验];

学科分类号：

100208 [临床检验诊断学];

摘要：

<正>功能性的维生素D主要包括维生素D3和维生素D2。维生素D除了具有传统意义上的骨骼效应,它还有着广泛的非骨骼效应,与心血管疾病、免疫疾病、糖尿病、肿瘤等疾病密切相关。25-羟基维生素D(25OHD)测定是衡量维生素D营养状态的最佳指标。根据测定原理不同,目前25OHD的测定方法可分为多种,液相色谱-串联质谱法(LC-MS/MS)具有特异性强、准确性高的特点,被认为是评价维生素D营养状况的"金标准"测定法。

引用

页码：3028 / 3030

页数：3

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