α-葡萄糖苷酶抑制剂治疗糖尿病的研究进展

被引：21

作者：

张远超

陆付耳

机构：

[1] 华中科技大学同济医学院附属同济医院

来源：

中国中西医结合消化杂志 | 2004年 / 02期

关键词：

糖尿病; α-葡萄糖苷酶抑制剂;

D O I：

暂无

中图分类号：

R587.1 [糖尿病];

学科分类号：

摘要：

<正>糖尿病是一组由遗传和环境因素相互作用而引起的临床综合征,系因胰岛素分泌绝对或相对不足及靶组织对胰岛素敏感性降低,引起机体糖、脂肪、蛋白质、水和电解质等一系列代谢紊乱,临床以高血糖为主要共同标志。久病可引起多系统损害,病情严重或应激时可发生急性代谢紊乱如酮症酸中毒等。

引用

页码：125 / 127

页数：3

共 7 条

[1] Acarbose improved severe postprandial hypotension in a patient with diabetes mellitus [J].

Sasaki, E ;

Goda, K ;

Nagata, K ;

Kitaoka, H ;

Ohsawa, N ;

Hanafusa, T .

JOURNAL OF DIABETES AND ITS COMPLICATIONS, 2001, 15 (03) :158-161

[2]

Effects of the α‐glucosidase inhibitor acarbose on the development of long‐term complications in diabetic animals: pathophysiological and therapeutic implications[J] . WernerCreutzfeldt.Diabetes Metab. Res. Rev. . 1999 (4)

[3] Acarbose-induced generalised erythema multiforme [J].

Kono, T ;

Hayami, M ;

Kobayashi, H ;

Ishii, M ;

Taniguchi, S .

LANCET, 1999, 354 (9176) :396-397

[4]

The PROTECT study: final results of a large multicenter postmarketing study in patients with type 2 diabetes[J] . John Buse,Kay Hart,Lori-ann Minasi.Clinical Therapeutics . 1998 (2)

[5] The effect of acarbose on insulin sensitivity and proinsulin in overweight subjects with impaired glucose tolerance [J].

Laube, H ;

Linn, T ;

Heyen, P .

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 1998, 106 (03) :231-233

[6]

Effect of an α-glucosidase inhibitor on glomerular basement membrane anionic sites in streptozotocin induced mildly diabetic rats[J] . Hiroko Sato,Noriko Shiina.Diabetes Research and Clinical Practice . 1997 (2)

[7]

Improvement of insulin sensitivity and dyslipidemia with a new α-glucosidase inhibitor, voglibose, in nondiabetic hyperinsulinemic subjects[J] . Kazuya Shinozaki,Masaaki Suzuki,Motoyoshi Ikebuchi,Junya Hirose,Yasushi Harano,Yutaka Harano.Metabolism . 1996 (6)

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