胶质瘤治疗中基因或药物载体的研究进展

被引：2

作者：

牛健

杨海城

机构：

[1] 哈尔滨医科大学附属第二医院神经外科

来源：

医学综述 | 2013年 / 01期

关键词：

胶质瘤; 纳米载体; 干细胞; 病毒载体;

D O I：

暂无

中图分类号：

R739.4 [神经系肿瘤];

学科分类号：

100115 [医学神经生物学];

摘要：

胶质瘤发病率占颅内肿瘤的第一位,临床上通常采用手术、放疗和化疗等综合治疗手段,但其疗效及预后较差,因而基因治疗或靶向性药物治疗成为学者研究的重点,用于胶质瘤治疗的基因或药物载体被大量发现和研究。目前,所使用的载体大致分为病毒性载体和非病毒性载体两大类。病毒性载体是最早被应用,也是应用最多的基因载体,然而大部分的病毒性载体在使用上存在很大的局限性,这使得纳米载体和干细胞等非病毒性载体研究的重要性日益显现。

引用

页码：65 / 69

页数：5

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