炎症性肠病合并难辨梭状芽孢杆菌感染的识别和治疗策略

被引：6

作者：

李玥

钱家鸣

机构：

[1] 中国医学科学院北京协和医学院北京协和医院消化科

来源：

胃肠病学和肝病学杂志 | 2016年 / 25卷 / 10期

关键词：

炎症性肠病; 难辨梭状芽孢杆菌; 危险因素; 治疗; 粪菌移植;

D O I：

暂无

中图分类号：

R574.62 [结肠疾病];

学科分类号：

100201 [内科学];

摘要：

难辨梭状芽孢杆菌感染(Clostridium difficile infection,CDI)在炎症性肠病(inflammatory bowel disease,IBD)患者中的发生率不断上升。CDI明显增加IBD患者预后不良,如死亡和结肠切除手术率。抗生素、治疗IBD的免疫抑制药物如激素等、年龄、合并症等均是CDI的高危因素。及时诊断CDI并给予恰当治疗是诊治的重点。

引用

页码：1088 / 1090

页数：3

共 14 条

[1]

Microbiome changes associated with sustained eradication of Clostridium difficile after single faecal microbiota transplantation in children with and without inflammatory bowel disease [J].

Hourigan, S. K. ;

Chen, L. A. ;

Grigoryan, Z. ;

Laroche, G. ;

Weidner, M. ;

Sears, C. L. ;

Oliva-Hemker, M. .

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2015, 42 (06) :741-752

[2]

Managing Clostridium difficile in Inflammatory Bowel Disease (IBD) [J].

Hashash J.G. ;

Binion D.G. .

Current Gastroenterology Reports, 2014, 16 (7)

[3]

Opportunistic Infections Due to Inflammatory Bowel Disease Therapy [J].

Dave, Maneesh ;

Purohit, Treta ;

Razonable, Raymund ;

Loftus, Edward V., Jr. .

INFLAMMATORY BOWEL DISEASES, 2014, 20 (01) :196-212

[4]

Clostridium difficile Infection in Newly Diagnosed Pediatric Inflammatory Bowel Disease in the Mid-Southern United States [J].

Mir, Sabina A. V. ;

Kellermayer, Richard .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2013, 57 (04) :487-488

[5]

Genetic risk factors for C lostridium difficile infection in ulcerative colitis.[J].A. N. Ananthakrishnan;E. C. Oxford;D. D. Nguyen;J. Sauk;V. Yajnik;R. J. Xavier.Aliment Pharmacol Ther.2013, 5

[6]

Transient Flare of Ulcerative Colitis After Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection [J].

De Leon, Lauren M. ;

Watson, James B. ;

Kelly, Colleen R. .

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2013, 11 (08) :1036-1038

[7]

Impact of Clostridium difficile colitis on 5‐year health outcomes in patients with ulcerative colitis.[J].S. K. Murthy;A. H. Steinhart;J. Tinmouth;P. C. Austin;N. Daneman;G. C. Nguyen.Aliment Pharmacol Ther.2012, 11pt

[8]

Repeat stool testing for Clostridium difficile using enzyme immunoassay in patients with inflammatory bowel disease increases diagnostic yield [J].

Deshpande, Abhishek ;

Pasupuleti, Vinay ;

Patel, Preethi ;

Pant, Chaitanya ;

Pagadala, Mangesh ;

Hall, Geraldine ;

Hu, Bo ;

Jain, Anil ;

Rolston, David D. K. ;

Sferra, Thomas J. ;

Atreja, Ashish .

CURRENT MEDICAL RESEARCH AND OPINION, 2012, 28 (09) :1553-1560

[9]

Infection-related hospitalizations are associated with increased mortality in patients with inflammatory bowel diseases.[J].Ashwin N. Ananthakrishnan;Emily L. McGinley.Journal of Crohn's and Colitis.2012,

[10]

Association Between Proton Pump Inhibitor Therapy and Clostridium difficile Infection in a Meta-Analysis [J].

Deshpande, Abhishek ;

Pant, Chaitanya ;

Pasupuleti, Vinay ;

Rolston, David D. K. ;

Jain, Anil ;

Deshpande, Narayan ;

Thota, Priyaleela ;

Sferra, Thomas J. ;

Hernandez, Adrian V. .

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2012, 10 (03) :225-233

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