c-FLIP与凋亡、信号转导途径

被引：4

作者：

宋敏 ^{[1
]}

陆化 ^{[2
]}

机构：

[1] 南京医科大学第二附属医院血液科

[2] 南京医科大学第一附属医院血液科

来源：

现代肿瘤医学 | 2010年 / 18卷 / 02期

关键词：

c-FLIP; 凋亡; 信号转导;

D O I：

暂无

中图分类号：

R363 [病理生理学];

学科分类号：

100103 [病原生物学];

摘要：

c-FLIP是一种凋亡抑制蛋白,能强效抑制Fas(CD95/APO-1)、TRAIL(肿瘤坏死因子相关凋亡诱导配体)-R1/R2(DR4/5)、TNFR1(肿瘤坏死因子受体)等死亡受体(DR)诱导的细胞凋亡,近年来发现其在多种凋亡、信号转导途径中发挥了凋亡抑制的作用。

引用

页码：408 / 413

页数：6

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