曲美他嗪对放化疗患者心血管保护作用的研究进展

被引：4

作者：

张丽英

吴绥生

机构：

[1] 吉林大学白求恩第一医院干部病房

来源：

中国老年学杂志 | 2012年 / 32卷 / 05期

关键词：

曲美他嗪; 放疗; 化疗药物; 心血管保护;

D O I：

暂无

中图分类号：

R730.5 [肿瘤治疗学];

学科分类号：

100214 [肿瘤学];

摘要：

<正>化疗、放疗、手术是临床治疗肿瘤的三大手段,为提高肿瘤治愈率,常联合应用。然而,放化疗不但杀伤肿瘤细胞,同时也对机体正常组织和细胞有杀伤作用。近年来,放化疗对心血管的损伤逐渐成为研究热点。1放化疗心血管损伤1.1概述化疗是目前治疗肿瘤及某些免疫性疾病的主要手段之一,但其副作用如脱发,消化障碍,骨髓抑制,心脏毒性,静

引用

收藏

页码：1096 / 1099

页数：4

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共 15 条

[1]

Tanshinone IIA sodium sulfonate protects against cardiotoxicity induced by doxorubicin in vitro and in vivo [J].

Jiang, Baohong ;

Zhang, Lin ;

Wang, Yingchun ;

Li, Ming ;

Wu, Wanying ;

Guan, Shuhong ;

Liu, Xuan ;

Yang, Min ;

Wang, Junchen ;

Guo, De-an .

FOOD AND CHEMICAL TOXICOLOGY, 2009, 47 (07) :1538-1544

[2]

Novel insights into pathological changes in muscular arteries of radiotherapy patients [J].

Russell, Nicola S. ;

Hoving, Saske ;

Heeneman, Sylvia ;

Hage, J. Joris ;

Woerdeman, Leonie A. E. ;

de Bree, Remco ;

Lohuis, Peter J. F. M. ;

Smeele, Ludi ;

Cleutjens, Jack ;

Valenkamp, Addy ;

Dorresteijn, Lucille D. A. ;

Dalesio, Otilia ;

Daemen, Mat J. ;

Stewart, Fiona A. .

RADIOTHERAPY AND ONCOLOGY, 2009, 92 (03) :477-483

[3]

Effect of trimetazidine on quality of life in elderly patients with ischemic dilated cardiomyopathy [J].

Marazzi, Giuseppe ;

Gebara, Otavio ;

Vitale, Cristiana ;

Caminiti, Giuseppe ;

Wajngarten, Mauricio ;

Volterrani, Maurizio ;

Ramires, Jose A. F. ;

Rosano, Giuseppe ;

Fini, Massimo .

ADVANCES IN THERAPY, 2009, 26 (04) :455-461

[4]

Single-dose and fractionated irradiation promote initiation and progression of atherosclerosis and induce an inflammatory plaque phenotype in ApoE-/- mice [J].

Hoving, Saske ;

Heeneman, Sylvia ;

Gijbels, Marion J. J. ;

Johannes, A. M. ;

Russell, Nicola S. ;

Daemen, Mat J. A. P. ;

Stewart, Fiona A. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2008, 71 (03) :848-857

[5]

Dexrazoxane protects against doxorubicin-induced cardiomyopathy: upregulation of Akt and Erk phosphorylation in a rat model [J].

Xiang, Ping ;

Deng, Hai Yan ;

Li, Karen ;

Huang, Guo-Ying ;

Chen, Yuan ;

Tu, Liu ;

Ng, Pak Cheung ;

Pong, Nga Hin ;

Zhao, Hailu ;

Zhang, Lei ;

Sung, Rita Yn Tz .

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2009, 63 (02) :343-349

[6]

Ionizing radiation accelerates the development of atherosclerotic lesions in ApoE-/- mice and predisposes to an inflammatory plaque phenotype prone to hemorrhage [J].

Stewart, FA ;

Heeneman, S ;

Poele, JT ;

Kruse, J ;

Russell, NS ;

Gijbels, M ;

Daemen, M .

AMERICAN JOURNAL OF PATHOLOGY, 2006, 168 (02) :649-658

[7]

The anti-anginal drug trimetazidine reduces neutrophil-mediated cardiac reperfusion injury [J].

Tritto, I ;

Wang, PH ;

Kuppusamy, P ;

Giraldez, R ;

Zweier, JL ;

Ambrosio, G .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2005, 46 (01) :89-98

[8]

Response of doxorubicin-induced cardiomyopathy to the current management strategy of heart failure [J].

Tallaj, JA ;

Franco, V ;

Rayburn, BK ;

Pinderski, L ;

Benza, RL ;

Pamboukian, S ;

Foley, B ;

Bourge, RC .

JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2005, 24 (12) :2196-2201

[9]

Increased carotid wall thickening after radiotherapy on the neck [J].

Dorresteijn, LDA ;

Kappelle, AC ;

Scholz, NMJ ;

Munneke, M ;

Scholma, JT ;

Balm, AJM ;

Bartelink, H ;

Boogerd, W .

EUROPEAN JOURNAL OF CANCER, 2005, 41 (07) :1026-1030

[10]

盐酸曲美他嗪对急性病毒性心肌炎的心肌保护作用观察 [J].

余浩 ;

李姣 .

心脏杂志, 2010, 22 (03) :406-407+411