Th9细胞和白细胞介素-9在自身免疫性疾病中的研究进展

被引：6

作者：

李晓倩

孙海英

乔建林

徐开林

机构：

[1] 徐州医学院附属医院血液科

来源：

国际免疫学杂志 | 2016年 / 39卷 / 02期

关键词：

Th9; 白细胞介素-9; 自身免疫性疾病;

D O I：

暂无

中图分类号：

R593.2 [自身免疫性疾病、结缔组织疾病];

学科分类号：

100201 [内科学];

摘要：

Th9细胞亚群是近几年发现的一种新型效应性CD4+T淋巴细胞亚群, 其主要以分泌细胞因子白细胞介素(IL)-9为特征。其分泌的IL-9可作用于不同的炎性细胞和组织细胞, 产生不同的生物学效应。研究显示, Th9细胞和IL-9参与许多自身免疫性疾病如自身免疫性肠炎、自身免疫性脑脊髓炎(EAE)、系统性红斑狼疮(SLE)、银屑病等的发病机理, 在疾病的发生和发展中起着重要的作用。

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