N端B型脑钠肽在脓毒症中的研究进展

被引：17

作者：

刘娟 ^{[1
,2
]}

肖政辉 ^{[2
]}

机构：

[1] 南华大学儿科学院

[2] 湖南省儿童医院急救中心

来源：

中国医师杂志 | 2013年 / 15卷 / 06期

关键词：

利钠肽,脑; 脓毒症; 综述;

D O I：

暂无

中图分类号：

R459.7 [急症、急救处理];

学科分类号：

100231 [临床病理学];

摘要：

<正>B型钠尿肽（brain natriuretic peptide,BNP）是一种心脏分泌的神经激素,是利钠肽类激素家族成员之一,具有利尿、扩血管、抑制肾素和醛固酮的释放、抑制心室和血管肌细胞的生长的作用。NT-proBNP是心力衰竭的公认标志物,据报道,在心衰、肺栓塞及由心肌缺血所致的心肌损伤中NT-proBNP水平升高[1-2。NT-proBNP和缺血性心肌病的关系是过去研究的焦点,最近脓毒症在促进心肌NTproBNP释放方面受到广泛关注,严重脓毒症或脓毒性休克

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