TRIM59在恶性肿瘤中的研究进展附视频

被引:8
作者
刘晓风
郑春燕
李燕京
孙秀威
机构
[1] 哈尔滨医科大学附属肿瘤医院
关键词
TRIM59; 肿瘤; 增殖; 迁移;
D O I
暂无
中图分类号
R730.2 [肿瘤病理学、病因学];
学科分类号
摘要
TRIM59(tripartite motif-containing 59)是一个新型的TRIM(tripartite motif)家族成员,与多种肿瘤有关。研究显示TRIM59作为癌基因,在肺癌、胃癌、肝癌、结直肠癌等肿瘤中表达上调;而且,TRIM59可通过多种途径促进肿瘤细胞的增殖和迁移。TRIM59有望成为肿瘤诊断和治疗的新靶点。
引用
收藏
页码:1098 / 1102
页数:5
相关论文
共 19 条
  • [1] TRIM59、Twist及E-cadherin在肝癌中的表达及临床意义
    薛栋
    王妮
    徐怀勇
    王建强
    夏修良
    [J]. 实用医学杂志, 2017, 33 (09) : 1453 - 1456
  • [2] 乳腺癌TGF-β信号通路相关转录因子研究进展
    周雨晴
    金敏
    祖旭宇
    [J]. 中华肿瘤防治杂志, 2016, 23 (15) : 1041 - 1048
  • [3] Therapeutic options for peritoneal metastasis arising from colorectal cancer
    Gabriel Glockzin
    Hans J Schlitt
    Pompiliu Piso
    [J]. World Journal of Gastrointestinal Pharmacology and Therapeutics, 2016, (03) : 343 - 352
  • [4] TRIM24介导肺癌细胞吉非替尼耐药机制探讨
    李海英
    王庆苓
    包海军
    张恒
    庄莹
    [J]. 中国肺癌杂志, 2016, 19 (01) : 24 - 29
  • [5] Epithelial–mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis[J] . Tong Chen,Yanan You,Hua Jiang,Zack Z. Wang.Journal of Cellular Physiology . 2017 (12)
  • [6] Knockdown of Tripartite-59 (TRIM59) Inhibits Cellular Proliferation and Migration in Human Cervical Cancer Cells
    Aierken, Gulijiahan
    Seyiti, Ayinuer
    Alifu, Mayinuer
    Kuerban, Gulina
    [J]. ONCOLOGY RESEARCH, 2017, 25 (03) : 381 - 388
  • [7] Identification of a synonymous variant in TRIM59 gene for gastric cancer risk in a Chinese population
    Luo, Dakui
    Wang, Younan
    Huan, Xiangkun
    Huang, Chi
    Yang, Chao
    Fan, Hao
    Xu, Zekuan
    Yang, Li
    [J]. ONCOTARGET, 2017, 8 (07) : 11507 - 11516
  • [8] TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis
    Chauhan, Santosh
    Kumar, Suresh
    Jain, Ashish
    Ponpuak, Marisa
    Mudd, Michal H.
    Kimura, Tomonori
    Choi, Seong Won
    Peters, Ryan
    Mandell, Michael
    Bruun, Jack-Ansgar
    Johansen, Terje
    Deretic, Vojo
    [J]. DEVELOPMENTAL CELL, 2016, 39 (01) : 13 - 27
  • [9] Cancer statistics in China, 2015[J] . Wanqing Chen,Rongshou Zheng,Peter D. Baade,Siwei Zhang,Hongmei Zeng,Freddie Bray,Ahmedin Jemal,Xue Qin Yu,Jie He.CA: A Cancer Journal for Clinicians . 2016 (2)
  • [10] TRIM59 Is Up-Regulated in Gastric Tumors, Promoting Ubiquitination and Degradation of P53[J] . Zhicheng Zhou,Zhongzhong Ji,You Wang,Jian Li,Hui Cao,Helen He Zhu,Wei-Qiang Gao.Gastroenterology . 2014