溃疡性结肠炎药物治疗的研究进展

被引:49
作者
李明明
王启之
机构
[1] 蚌埠医学院第一附属医院消化内科
关键词
溃疡性结肠炎; 免疫抑制剂; 生物制剂; 治疗;
D O I
暂无
中图分类号
R574.62 [结肠疾病];
学科分类号
100201 [内科学];
摘要
溃疡性结肠炎(ulcerative colitis,UC)作为一种自身免疫性疾病,其发生及发展机制尚未明确,但相关研究表明免疫因素在UC发生、发展及愈后的过程中起重要作用。关于UC的治疗,临床常用的方法是药物治疗,其中免疫抑制剂及生物制剂在中、重度UC的治疗中起重要作用。本文主要对近年来国内外有关新型免疫抑制剂及生物制剂在UC治疗方面的疗效作一概述。
引用
收藏
页码:458 / 461
页数:4
相关论文
共 14 条
[1]
Role of moxibustion in inflammatory responses during treatment of rat ulcerative colitis [J].
Han, Yang ;
Ma, Tie-Ming ;
Lu, Mao-Lin ;
Ren, Lu ;
Ma, Xian-De ;
Bai, Zeng-Hua .
WORLD JOURNAL OF GASTROENTEROLOGY, 2014, 20 (32) :11297-11304
[2]
高效免疫抑制剂在炎性肠病中的应用 [J].
徐子鹏 ;
胡金玉 .
吉林医学, 2013, 34 (13) :2447-2449
[3]
235例炎症性肠病患者首次接受糖皮质激素治疗的临床疗效分析 [J].
陈白莉 ;
陈瑜君 ;
高翔 ;
何瑶 ;
肖英莲 ;
陈旻湖 ;
胡品津 .
胃肠病学和肝病学杂志, 2013, 22 (01) :66-70
[4]
英夫利昔单抗-类克在激素抵抗及激素依赖溃疡性结肠炎治疗中的应用.[J].李懿璇;李世荣;李俊霞;杨欣艳;王化虹;.世界华人消化杂志.2012, 21
[5]
Use of mycophenolate mofetil in inflammatory bowel disease [J].
Tan, Terrence ;
Lawrance, Ian Craig .
WORLD JOURNAL OF GASTROENTEROLOGY, 2009, 15 (13) :1594-1599
[6]
A Comparison of Short- and Long-Term Therapeutic Outcomes of Infliximab- versus Tacrolimus-Based Strategies for Steroid-Refractory Ulcerative Colitis.[J].Katsuya Endo;Motoyuki Onodera;Hisashi Shiga;Masatake Kuroha;Tomoya Kimura;Keiichiro Hiramoto;Yoichi Kakuta;Yoshitaka Kinouchi;Tooru Shimosegawa;Per Hellstr?m.Gastroenterology Research and Practice.2016,
[7]
Association Between Serum Concentration of Infliximab and Efficacy in Adult Patients With Ulcerative Colitis [J].
Adedokun, Omoniyi J. ;
Sandborn, William J. ;
Feagan, Brian G. ;
Rutgeerts, Paul ;
Xu, Zhenhua ;
Marano, Colleen W. ;
Johanns, Jewel ;
Zhou, Honghui ;
Davis, Hugh M. ;
Cornillie, Freddy ;
Reinisch, Walter .
GASTROENTEROLOGY, 2014, 147 (06) :1296-+
[8]
Ability of different rescue therapies to save the bowel in acute, severe, steroid-refractory ulcerative colitis [J].
Farkas, Klaudia ;
Molnar, Tamas ;
Szepes, Zoltan .
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 2014, 8 (06) :695-702
[9]
Systematic review of the effectiveness of biological therapy for active moderate to severe ulcerative colitis [J].
Kawalec, Pawel ;
Mikrut, Alicja ;
Lopuch, Sylwia .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2014, 29 (06) :1159-1170
[10]
Mycophenolate mofetil therapy in the management of inflammatory bowel disease - A retrospective case series and review [J].
Smith, Matthew R. ;
Cooper, Sheldon C. .
JOURNAL OF CROHNS & COLITIS, 2014, 8 (08) :890-897