脂肪因子与代谢综合征

被引:36
作者
张鹏
汪南平
机构
[1] 北京大学心血管研究所分子心血管学教育部重点实验室
关键词
脂肪因子; 代谢综合征;
D O I
暂无
中图分类号
R589 [代谢病];
学科分类号
100201 [内科学];
摘要
脂肪因子是一系列由脂肪组织分泌的生物活性物质,包括瘦素、抵抗素、脂联素、内肥素、肿瘤坏死因子、纤溶酶原激活物抑制因子和白介素-6等。脂肪因子的紊乱参与肥胖、糖尿病及动脉粥样硬化等多种代谢性疾病的发病过程。本文将着重讨论脂肪因子与代谢综合征的关联。
引用
收藏
页码:21 / 26
页数:6
相关论文
共 5 条
[1]
Leptin resistance exacerbates diet-induced obesity and is associated with diminished maximal leptin signalling capacity in rats [J].
Scarpace, P ;
Matheny, M ;
Tümer, N ;
Cheng, KY ;
Zhang, Y .
DIABETOLOGIA, 2005, 48 (06) :1075-1083
[2]
Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes [J].
Hamid, YH ;
Rose, CS ;
Urhammer, SA ;
Glümer, C ;
Nolsoe, R ;
Kristiansen, OP ;
Mandrup-Poulsen, T ;
Borch-Johnsen, K ;
Jorgensen, T ;
Hansen, T ;
Pedersen, O .
DIABETOLOGIA, 2005, 48 (02) :251-260
[3]
Short-term infusion of interleukin-6 does not induce insulin resistance in vivo or impair insulin signalling in rats [J].
Sopasakis, VR ;
Larsson, BM ;
Johansson, A ;
Holmäng, A ;
Smith, U .
DIABETOLOGIA, 2004, 47 (11) :1879-1887
[4]
Interleukin-6 and insulin sensitivity: friend or foe? [J].
Carey, AL ;
Febbraio, MA .
DIABETOLOGIA, 2004, 47 (07) :1135-1142
[5]
Interleukin-6 and tumor necrosis factor-α are not increased in patients with Type 2 diabetes:: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness [J].
Carey, AL ;
Bruce, CR ;
Sacchetti, M ;
Anderson, MJ ;
Olsen, DB ;
Saltin, B ;
Hawley, JA ;
Febbraio, MA .
DIABETOLOGIA, 2004, 47 (06) :1029-1037