金钱草颗粒对胆囊结石患者血清CCK-A和VIP水平的影响

被引：21

作者：

张平

李春田

马明

张伟

李晓英

机构：

[1] 解放军第四六三医院放疗科

来源：

现代生物医学进展 | 2015年 / 15卷 / 27期

关键词：

金钱草颗粒; 胆囊结石; 胆囊收缩素受体; 血管活性肠肽;

D O I：

10.13241/j.cnki.pmb.2015.27.028

中图分类号：

R575.62 [];

学科分类号：

摘要：

目的:探究金钱草颗粒对胆囊结石患者血清胆囊收缩素受体(CCK-A)和血管活性肠肽(VIP)含量的影响。方法:选取我院普外科收治的胆囊结石患者218例,采用双盲法将其分为实验组和对照组。对照组给予口服消炎利胆片和熊去氧胆酸片治疗,而实验组给予金钱草颗粒和熊去氧胆酸片治疗。检测和比较两组患者治疗前后血清CCK-A和VIP含量以及胆囊结石数目、直径的变化情况。结果:治疗后,两组患者胆囊结石数目、直径及血清VIP含量均较治疗前显著减少或降低,且实验组显著低于对照组,差异均具有统计学意义(P<0.05);而两组患者的血清CCK-A含量均较治疗前明显升高,且实验组显著高于对照组,差异具有统计学意义(P<0.05)。结论:金钱草颗粒可有效减少胆囊结石患者的结石大小和数目,这可能与其提高患者血清CCK-A含量以及降低血清VIP含量有关。

引用

页码：5306 / 5308

页数：3

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