肌少症中骨骼肌质量减少的分子机制研究进展

被引：14

作者：

杨琦琦

孙颖

机构：

[1] 首都医科大学附属北京友谊医院老年医学科

来源：

临床和实验医学杂志 | 2020年 / 19卷 / 09期

关键词：

肌少症; 骨骼肌减少; 分子机制;

D O I：

暂无

中图分类号：

R685 [肌肉疾病及损伤];

学科分类号：

100220 [骨科学];

摘要：

<正>肌少症,亦称骨骼肌减少症,是由Rosenberg（1997）首先提出的一种新的老年综合征,是仅与年龄相关的进行性和全身性的骨骼肌疾病,与跌倒、骨折、失能和死亡等不良预后的风险增加相关。2014年亚洲肌少症工作组（Asia Working Group for Sarcopenia,AWGS）将肌少症定义为年龄相关的骨骼肌质量、力量的丧失和（或）功能的减退[1],老年人肌少症的患病率为4. 1%～11. 5%[1]。随着全球老龄化的进展,肌少症是未来将要面临的主要健康问题之一。骨骼肌在维持代谢稳态方面也起着十

引用

页码：1006 / 1009

页数：4

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