肿瘤坏死因子-α在骨关节结核中的研究进展

被引：10

作者：

梁思敏 ^{[1
]}

蔡则成 ^{[2
]}

马赫 ^{[2
]}

戈朝晖 ^{[1
]}

机构：

[1] 宁夏医科大学总医院脊柱骨科

[2] 宁夏医科大学

来源：

宁夏医科大学学报 | 2018年 / 40卷 / 01期

关键词：

结核病; 骨和关节结核; 肿瘤坏死因子;

D O I：

10.16050/j.cnki.issn1674-6309.2018.01.034

中图分类号：

R529.2 [骨和关节结核];

学科分类号：

100201 [内科学];

摘要：

<正>肿瘤坏死因子-α（tumor necrosis factor-alpha,TNF-α）是由活化的巨噬细胞分泌产生的一种多效性细胞因子,参与细胞增殖分化、炎症反应、免疫调节等多种生理病理过程,与恶性肿瘤、炎性疾病、自身免疫性疾病以及感染性疾病的发生发展密切相关[1]。骨关节结核是肺外结核的主要表现形式,占肺外结核总数的35%～50%[2],此病是由结核分枝杆菌经过血液系统或者淋巴系统侵及骨关节,引起骨质破坏、死骨形成的一种慢性

引用

页码：115 / 121

页数：7

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