五羟色胺转运体的研究进展

被引:29
作者
范东芬
奚耕思
梁开丹
张武会
机构
[1] 陕西师范大学生命科学学院动物生殖与发育实验室
关键词
五羟色胺; 五羟色胺转运体; 基因多态性; 抑郁症;
D O I
10.13376/j.cbls/2011.04.005
中图分类号
R741 [神经病学];
学科分类号
100204 [神经病学];
摘要
五羟色胺转运体是一种对五羟色胺(5-HT,serotonin)有高度亲和力的跨膜转运蛋白,能够重新摄取细胞间隙内的5-HT,从而调节神经信号的转导。该文简述了五羟色胺转运体的生物学特性、分布以及与人类疾病的关系,通过分析比较发现,五羟色胺转运体的多态性与肠易激综合征、抑郁症、强迫症都有着密切的关系。
引用
收藏
页码:385 / 389
页数:5
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