中国脓毒症/脓毒性休克急诊治疗指南(2018)

被引：696

作者：

曹钰

柴艳芬

邓颖

方邦江

刘明华

卢中秋

陆一鸣

聂时南

钱传云

田英平

杨立山

姚咏明

尹文

于学忠

张新超

赵敏

赵晓东

周荣斌

朱华栋

朱曦

曾红科

机构：

[1] 中国医师协会急诊医师分会

[2] 中国研究型医院学会休克与脓毒症专业委员会

[3] 中国人民解放军总医院第一附属医院创伤研究中心

[4] 北京协和医院急诊科

[5] 中国人民解放军陆军总医院急诊科

来源：

临床急诊杂志 | 2018年 / 19卷 / 09期

关键词：

脓毒症; 推荐意见; 脓毒性休克; 液体复苏; 急诊治疗;

D O I：

10.13201/j.issn.1009-5918.2018.09.001

中图分类号：

R459.7 [急症、急救处理];

学科分类号：

100218 ;

摘要：

<正>脓毒症和脓毒性休克是急危重症医学面临的重要临床问题,全球每年脓毒症患病人数超过1 900万,其中有600万患者死亡,病死率超过1/4,存活的患者中约有300万人存在认知功能障碍[1-3]。早期识别与恰当处理可改善脓毒症患者的预后。近年来,国内外对脓毒症领域的研究不断深入,临床实践及证据不断增加,2016年美国重症医学会(SCCM)与欧洲重症医学会(ESICM)联合发布脓毒症3.0定义及诊断标准,新定义的出现及临床证据的积累都会对临床决策产生重要影响。为了更好地指导

引用

页码：567 / 588

页数：22

共 151 条

[61] Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America
Freifeld, Alison G.
Bow, Eric J.
Sepkowitz, Kent A.
Boeckh, Michael J.
Ito, James I.
Mullen, Craig A.
Raad, Issam I.
Rolston, Kenneth V.
Young, Jo-Anne H.
Wingard, John R.
[J]. CLINICAL INFECTIOUS DISEASES, 2011, 52 (04) : E56 - E93
[62] Systematic Review and Meta-Analysis of the Efficacy of Appropriate Empiric Antibiotic Therapy for Sepsis
Paul, Mical
Shani, Vered
Muchtar, Eli
Kariv, Galia
Robenshtok, Eyal
Leibovici, Leonard
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2010, 54 (11) : 4851 - 4863
[63] Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: A propensity-matched analysis
Kumar, Anand
Zarychanski, Ryan
Light, Bruce
Parrillo, Joseph
Maki, Dennis
Simon, Dave
Laporta, Denny
Lapinsky, Steve
Ellis, Paul
Mirzanejad, Yazdan
Martinka, Greg
Keenan, Sean
Wood, Gordon
Arabi, Yaseen
Feinstein, Daniel
Kumar, Aseem
Dodek, Peter
Kravetsky, Laura
Doucette, Steve
[J]. CRITICAL CARE MEDICINE, 2010, 38 (09) : 1773 - 1785
[64] A survival benefit of combination antibiotic therapy for serious infections associated with sepsis and septic shock is contingent only on the risk of death: A meta-analytic/meta-regression study
Kumar, Anand
Safdar, Nasia
Kethireddy, Shravan
Chateau, Dan
[J]. CRITICAL CARE MEDICINE, 2010, 38 (08) : 1651 - 1665
[65] A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.[J]..The Lancet.2010, 9713
[66] Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial.[J]..The Lancet.2010, 9713
[67] Comparison of norepinephrine and dobutamine to epinephrine for hemodynamics, lactate metabolism, and gastric tonometric variables in septic shock: A prospective, randomized study
Levy, B
Bollaert, PE
Charpentier, C
Nace, L
Audibert, G
Bauer, P
Nabet, P
Larcan, A
[J]. INTENSIVE CARE MEDICINE, 1997, 23 (03) : 282 - 287
[68] Vasopressin deficiency contributes to the vasodilation of septic shock
Landry, DW
Levin, HR
Gallant, EM
Ashton, RC
Seo, S
DAlessandro, D
Oz, MC
Oliver, JA
[J]. CIRCULATION, 1997, 95 (05) : 1122 - 1125
[69] Oxygen delivery, oxygen consumption, and gastric intramucosal pH are not improved by a computer-controlled, closed-loop, vecuronium infusion in severe sepsis and septic shock
Freebairn, RC
Derrick, J
Gomersall, CD
Young, RJ
Joynt, GM
[J]. CRITICAL CARE MEDICINE, 1997, 25 (01) : 72 - 77
[70] Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously
Ely, EW
Baker, AM
Dunagan, DP
Burke, HL
Smith, AC
Kelly, PT
Johnson, MM
Browder, RW
Bowton, DL
Haponik, EF
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (25) : 1864 - 1869

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