抑郁症动物模型建立及评价的研究进展

被引：31

作者：

叶娜 ^{[1
]}

郑卫英 ^{[2
]}

机构：

[1] 首都医科大学第五临床医学院

[2] 首都医科大学生物医学工程学院

来源：

数理医药学杂志 | 2015年 / 28卷 / 06期

关键词：

抑郁症; 动物模型; 模型评价;

D O I：

暂无

中图分类号：

R749.4 [情感性精神病]; R-332 [医用实验动物学];

学科分类号：

100204 [神经病学]; 100402 [劳动卫生与环境卫生学];

摘要：

随着人们生活节奏的加快,抑郁症患病率逐年增高。但由于其发病机制至今仍尚未明确,再加上无法用实验动物模拟及测评一些人类抑郁症的核心症状(如抑郁情绪、无用感,及反复出现的自杀的想法等),抑郁症的研究困难重重。主要综述目前使用较广泛的各型抑郁症动物模型建立方法,以及相关的行为学评价、认知功能检测方法,并对它们的优点与不足进行讨论。

引用

页码：902 / 904

页数：3

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