TGF-β/BMP信号通路在骨关节炎软骨细胞退变中的作用机制

被引：23

作者：

兰平文 ^{[1
]}

沈彬 ^{[2
]}

机构：

[1] 德阳市人民医院骨科

[2] 四川大学华西医院骨科

来源：

中华关节外科杂志(电子版) | 2015年 / 9卷 / 05期

关键词：

D O I：

暂无

中图分类号：

R684.3 [关节炎];

学科分类号：

100220 [骨科学];

摘要：

<正>骨关节炎(osteoarthritis,OA)是老年人群的常见病和多发病。根据流行病学调查,65岁以上的人群中的OA发病率男性为60%,女性为70%[1,2]。但OA的发病机制目前尚不完全清楚,软骨细胞退变是OA发病机制中的重要环节,在这一过程中转化生长因子-β(transforming growth factor-β,TGF-β)和骨形成蛋白(bone morphogenetic protein,BMP)信

引用

页码：644 / 647

页数：4

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