促甲状腺激素与脂肪细胞因子、糖尿病关系的研究进展

被引：5

作者：

孙霞 ^{[1
,2
]}

汪大望 ^{[3
]}

机构：

[1] 丽水市中心医院内分泌科

[2] 丽水市中医院

[3] 温州医科大学附属第一医院内分泌科

来源：

浙江医学 | 2018年 / 40卷 / 23期

关键词：

促甲状腺激素; 脂肪细胞因子; 糖尿病;

D O I：

暂无

中图分类号：

R587.1 [糖尿病];

学科分类号：

100201 [内科学];

摘要：

超重和肥胖是糖尿病的重要危险因素,肥胖与2型糖尿病(T2DM)发病以及心血管病变发生的风险增加显著相关。近年来研究表明促甲状腺激素的受体(TSHR)是脂肪细胞分化的重要的调节因子,脂肪组织中TSHR的异常表达与肥胖相关。目前TSHR在脂肪细胞的信号网络及其下游通路中的作用仍未研究清楚,且国内外有关T2DM人群促甲状腺激素(TSH)与脂肪细胞因子关系的研究也少有报道。本文就TSH与肥胖、脂肪细胞因子、T2DM关系的研究进展作一综述。

引用

收藏

页码：2615 / 2617

页数：3

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