羟基磷灰石基复合骨修复材料研究进展

被引:23
作者
陈涛 [1 ,2 ]
付海洋 [1 ]
李岩 [2 ]
付步芳 [1 ]
机构
[1] 中国食品药品检定研究院
[2] 北京航空航天大学材料科学与工程学院
关键词
骨修复; 羟基磷灰石; 复合材料; 载药;
D O I
10.16153/j.1002-7777.2019.03.011
中图分类号
R318.08 [生物材料学];
学科分类号
100103 [病原生物学];
摘要
羟基磷灰石因为接近骨组织成分,具有优良的生物相容性,而被广泛应用于骨修复领域。由于单一材料不具有多种优异的生物学性能,因此,制备性能优越的羟基磷灰石/聚合物复合骨修复材料成为骨修复材料领域的热点之一。本文综述了设计羟基磷灰石基复合骨修复材料的一些要点,总结了近几年国内外羟基磷灰石/聚合物复合材料的研究状况,并介绍了载药羟基磷灰石骨修复材料的研究情况,最后对羟基磷灰石基复合骨修复材料的发展提出展望。
引用
收藏
页码:302 / 309
页数:8
相关论文
共 41 条
[1]
纳米羟基磷灰石/聚酰胺/壳聚糖复合骨修复材料研究 [D]. 
向鸿照 .
四川大学,
2007
[2]
Calcium phosphates in biomedical applications: materials for the future? [J].
Habraken, Wouter ;
Habibovic, Pamela ;
Epple, Matthias ;
Bohner, Marc .
MATERIALS TODAY, 2016, 19 (02) :69-87
[3]
Ultrahigh strength of three-dimensional printed diluted magnesium doping wollastonite porous scaffolds [J].
Xie, Jiajun ;
Shao, Huifeng ;
He, Dongshuang ;
Yang, Xianyan ;
Yao, Chunlei ;
Ye, Juan ;
He, Yong ;
Fu, Jianzhong ;
Gou, Zhongru .
MRS COMMUNICATIONS, 2015, 5 (04) :631-639
[4]
Substituted hydroxyapatites for biomedical applications: A review [J].
Supova, Monika .
CERAMICS INTERNATIONAL, 2015, 41 (08) :9203-9231
[5]
Modification of polylactic acid surface using RF plasma discharge with sputter deposition of a hydroxyapatite target for increased biocompatibility.[J].S.I. Tverdokhlebov;E.N. Bolbasov;E.V. Shesterikov;L.V. Antonova;A.S. Golovkin;V.G. Matveeva;D.G. Petlin;Y.G. Anissimov.Applied Surface Science.2015,
[6]
Systematic approach to treat chronic osteomyelitis through localized drug delivery system: Bench to bed side [J].
Bhattacharya, Rupnarayan ;
Kundu, Biswanath ;
Nandi, Samit Kumar ;
Basu, Debabrata .
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2013, 33 (07) :3986-3993
[7]
The treatment of segmental bone defects in rabbit tibiae with vascular endothelial growth factor (VEGF)-loaded gelatin/hydroxyapatite "cryogel" scaffold [J].
Ozturk B.Y. ;
Inci I. ;
Egri S. ;
Ozturk A.M. ;
Yetkin H. ;
Goktas G. ;
Elmas C. ;
Piskin E. ;
Erdogan D. .
European Journal of Orthopaedic Surgery & Traumatology, 2013, 23 (7) :767-774
[8]
Fabrication and characterization of biomimetic collagen–apatite scaffolds with tunable structures for bone tissue engineering.[J].Zengmin Xia;Xiaohua Yu;Xi Jiang;Harold D. Brody;David W. Rowe;Mei Wei.Acta Biomaterialia.2013, 7
[9]
In vivo evaluation of porous hydroxyapatite/chitosan–alginate composite scaffolds for bone tissue engineering.[J].Hyeong-Ho Jin;Dong-Hyun Kim;Tae-Wan Kim;Keun-Koo Shin;Jin Sup Jung;Hong-Chae Park;Seog-Young Yoon.International Journal of Biological Macromolecules.2012, 5
[10]
In vitro characterizations of mesoporous hydroxyapatite as a controlled release delivery device for VEGF in orthopedic applications [J].
Poh, Chye Khoon ;
Ng, Suxiu ;
Lim, Tee Yong ;
Tan, Hark Chuan ;
Loo, Joachim ;
Wang, Wilson .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2012, 100A (11) :3143-3150