Rheumatoid Arthritis - Common Origins, Divergent Mechanisms

被引:513
作者
Gravallese, Ellen M. [1 ]
Firestein, Gary S. [2 ]
机构
[1] Brigham & Womens Hosp, Div Rheumatol Inflammat & Immun, Boston, MA USA
[2] Univ Calif San Diego, Div Rheumatol Allergy & Immunol, Sch Med, La Jolla, CA USA
关键词
MODIFYING ANTIRHEUMATIC DRUGS; AMERICAN-COLLEGE; SYNOVIAL TISSUE; BONE EROSION; DISEASE; RISK; ASSOCIATION; AUTOANTIBODIES; RECOMMENDATIONS; SYNOVIOCYTES;
D O I
10.1056/NEJMra2103726
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
[No abstract available]
引用
收藏
页码:529 / 542
页数:14
相关论文
共 92 条
[1]
Prediction of flare following remission and treatment withdrawal in early rheumatoid arthritis: post hoc analysis of a phase IIIb trial with abatacept [J].
Ahmad, Harris A. ;
Baker, Joshua F. ;
Conaghan, Philip G. ;
Emery, Paul ;
Huizinga, Thomas W. J. ;
Elbez, Yedid ;
Banerjee, Subhashis ;
Ostergaard, Mikkel .
ARTHRITIS RESEARCH & THERAPY, 2022, 24 (01)
[2]
Distinct DNA Methylation Patterns of Rheumatoid Arthritis Peripheral Blood and Synovial Tissue T Cells [J].
Ai, Rizi ;
Boyle, David L. ;
Wang, Wei ;
Firestein, Gary S. .
ACR OPEN RHEUMATOLOGY, 2021, 3 (03) :127-132
[3]
Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes [J].
Ai, Rizi ;
Hammaker, Deepa ;
Boyle, David L. ;
Morgan, Rachel ;
Walsh, Alice M. ;
Fan, Shicai ;
Firestein, Gary S. ;
Wang, Wei .
NATURE COMMUNICATIONS, 2016, 7
[4]
DNA Methylome Signature in Synoviocytes From Patients With Early Rheumatoid Arthritis Compared to Synoviocytes From Patients With Longstanding Rheumatoid Arthritis [J].
Ai, Rizi ;
Whitaker, John W. ;
Boyle, David L. ;
Tak, Paul Peter ;
Gerlag, Danielle M. ;
Wang, Wei ;
Firestein, Gary S. .
ARTHRITIS & RHEUMATOLOGY, 2015, 67 (07) :1978-1980
[5]
Systems-biology analysis of rheumatoid arthritis fibroblast-like synoviocytes implicates cell line-specific transcription factor function [J].
Ainsworth, Richard, I ;
Hammaker, Deepa ;
Nygaard, Gyrid ;
Ansalone, Cecilia ;
Machado, Camilla ;
Zhang, Kai ;
Zheng, Lina ;
Carrillo, Lucy ;
Wildberg, Andre ;
Kuhs, Amanda ;
Svensson, Mattias N. D. ;
Boyle, David L. ;
Firestein, Gary S. ;
Wang, Wei .
NATURE COMMUNICATIONS, 2022, 13 (01)
[6]
Seronegative and seropositive RA: alike but different? [J].
Ajeganova, Sofia ;
Huizinga, Tom W. J. .
NATURE REVIEWS RHEUMATOLOGY, 2015, 11 (01) :9-10
[7]
2010 Rheumatoid Arthritis Classification Criteria An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative [J].
Aletaha, Daniel ;
Neogi, Tuhina ;
Silman, Alan J. ;
Funovits, Julia ;
Felson, David T. ;
Bingham, Clifton O., III ;
Birnbaum, Neal S. ;
Burmester, Gerd R. ;
Bykerk, Vivian P. ;
Cohen, Marc D. ;
Combe, Bernard ;
Costenbader, Karen H. ;
Dougados, Maxime ;
Emery, Paul ;
Ferraccioli, Gianfranco ;
Hazes, Johanna M. W. ;
Hobbs, Kathryn ;
Huizinga, Tom W. J. ;
Kavanaugh, Arthur ;
Kay, Jonathan ;
Kvien, Tore K. ;
Laing, Timothy ;
Mease, Philip ;
Menard, Henri A. ;
Moreland, Larry W. ;
Naden, Raymond L. ;
Pincus, Theodore ;
Smolen, Josef S. ;
Stanislawska-Biernat, Ewa ;
Symmons, Deborah ;
Tak, Paul P. ;
Upchurch, Katherine S. ;
Vencovsky, Jiri ;
Wolfe, Frederick ;
Hawker, Gillian .
ARTHRITIS AND RHEUMATISM, 2010, 62 (09) :2569-2581
[8]
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis [J].
Alivernini, Stefano ;
MacDonald, Lucy ;
Elmesmari, Aziza ;
Finlay, Samuel ;
Tolusso, Barbara ;
Gigante, Maria Rita ;
Petricca, Luca ;
Di Mario, Clara ;
Bui, Laura ;
Perniola, Simone ;
Attar, Moustafa ;
Gessi, Marco ;
Fedele, Anna Laura ;
Chilaka, Sabarinadh ;
Somma, Domenico ;
Sansom, Stephen N. ;
Filer, Andrew ;
McSharry, Charles ;
Millar, Neal L. ;
Kirschner, Kristina ;
Nerviani, Alessandra ;
Lewis, Myles J. ;
Pitzalis, Costantino ;
Clark, Andrew R. ;
Ferraccioli, Gianfranco ;
Udalova, Irina ;
Buckley, Christopher D. ;
Gremese, Elisa ;
McInnes, Iain B. ;
Otto, Thomas D. ;
Kurowska-Stolarska, Mariola .
NATURE MEDICINE, 2020, 26 (08) :1295-+
[9]
Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis [J].
Baecklund, E ;
Iliadou, A ;
Askling, J ;
Ekborn, A ;
Backlin, C ;
Granath, F ;
Catrina, AT ;
Rosenquist, R ;
Feltelius, N ;
Sundström, C ;
Klareskog, L .
ARTHRITIS AND RHEUMATISM, 2006, 54 (03) :692-701
[10]
MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity [J].
Cai, Bishuang ;
Kasikara, Canan ;
Doran, Amanda C. ;
Ramakrishnan, Rajasekhar ;
Birge, Raymond B. ;
Tabas, Ira .
SCIENCE SIGNALING, 2018, 11 (549)