Optical Doppler tomography

被引:137
作者
Chen, ZP [1 ]
Zhao, YH
Srinivas, SM
Nelson, JS
Prakash, N
Frostig, RD
机构
[1] Univ Calif Irvine, Beckman Laser Inst, Irvine, CA 92612 USA
[2] Univ Calif Irvine, Dept Psychobiol, Irvine, CA 92612 USA
基金
美国国家卫生研究院;
关键词
biomedical image; Doppler flowmetry; optical Doppler tomography; optical coherence tomography;
D O I
10.1109/2944.796340
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Optical Doppler tomography (ODT) is an imaging modality that takes advantage of the short coherence length of a broad-band light sources to perform micrometer-scale, cross-sectional imaging of tissue structure and blood flow dynamics simultaneously. We review in this paper the principal of ODT and its applications. Results from in vitro and in vivo model studies demonstrated that ODT can map the blood flow velocity profile with high spatial resolution in scattering medium. ODT detection mechanisms are illustrated using Monte Carlo simulations. The application of ODT to image brain hemodynamics is demonstrated, Finally, we discuss the limitations of the current technology and application of a phase resolved technique to improve image speed and quality.
引用
收藏
页码:1134 / 1142
页数:9
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