Asymmetric synthesis of β-amino acid scaffolds

被引：25

作者：

Bull, SD ^{[1
]}

Davies, SG ^{[1
]}

Smith, AD ^{[1
]}

机构：

[1] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2001年 / Royal Society of Chemistry卷 / 22期

关键词：

D O I：

10.1039/b107440g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of two or three equivalents of lithium (S)-N-benzyl-N-alpha -methylbenzylamide to conjugate acceptors containing two or three alpha,beta -unsaturated ester fragments respectively and subsequent hydrogenolytic deprotection a ord homochiral bis- or tris-beta -amino esters containing two or three new stereogenic centres in high de and ee.

引用

页码：2931 / 2938

页数：8

共 48 条

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