In this study, surface and radiosonde data from staffed Antarctic observation stations are compared to output from five reanalyses [Climate Forecast System Reanalysis (CFSR), 40-yr ECMWF Re-Analysis (ERA-40), ECMWF Interim Re-Analysis (ERA-Interim), Japanese 25-year Reanalysis (JRA-25), and Modern Era Retrospective-Analysis for Research and Applications (MERRA)] over three decades spanning 1979-2008. Bias and year-to-year correlation between the reanalyses and observations are assessed for four variables: mean sea level pressure (MSLP), near-surface air temperature (T-s), 500-hPa geopotential height (H-500), and 500-hPa temperature (T-500). It was found that CFSR and MERRA are of a sufficiently high resolution for the height of the orography to be accurately reproduced at coastal observation stations. Progressively larger negative T-s biases at these coastal stations are apparent for reanalyses in order of decreasing resolution. However, orography height bias cannot explain large winter warm biases in CFSR. JRA-25, and MERRA (11.1 degrees, 10.2 degrees, and 7.9 degrees C, respectively) at Amundsen-Scott and Vostok, which have been linked to problems with representing the surface energy balance. Linear trends in the annual-mean T-500 and H-500 averaged over Antarctica as a whole were found to be most reliable in CFSR, ERA-Interim, and MERRA, none of which show significant trends over the period 1979-2008. In contrast JRA-25 shows significant negative trends over 1979-2008 and ERA-40 gives significant positive trends during the 1980s (evident in both T-500 and H-500). Comparison to observations indicates that the positive trend in ERA-40 is spurious. At the smaller spatial scale of individual stations all five reanalyses have some spurious trends. However, ERA-Interim was found to be the most reliable for MSLP and H-500 trends at station locations.