Synthesis of spiroquinolines through a one-pot multicatalytic and multicomponent cascade reaction

被引：72

作者：

Barluenga, Jose ^{[1
]}

Mendoza, Abraham ^{[1
]}

Rodriguez, Felix ^{[1
]}

Fananas, Francisco J. ^{[1
]}

机构：

[1] Univ Oviedo, Inst Univ Quim Organomet Enrique Moles, Unidad Asociada CSIC, E-33006 Oviedo, Spain

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 37期

关键词：

cyclization; homogeneous catalysis; multicomponent; reactions; platinum; quinolines;

D O I：

10.1002/anie.200802582

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Three's company: Functionalized spirocyclic quinoline derivatives are easily synthesized in a one-pot three-component coupling process involving the reaction of alkynol, aldehyde, and aniline derivatives (see scheme). The process is carried out in the presence of catalytic amounts of a platinum(II) complex and a protic acid. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：7044 / 7047

页数：4

共 59 条

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