MicroRNAs as therapeutic targets

被引：112

作者：

Czech, MP ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Worcester, MA 01605 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2006年 / 354卷 / 11期

关键词：

D O I：

10.1056/NEJMcibr060065

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Studies have tested the therapeutic value of small inhibitory RNAs by introducing them to an animal model of disease. A new study takes the opposite tack: a specific endogenous inhibitory RNA is ablated in the mouse, resulting in a large decrease in serum cholesterol. Copyright © 2006 Massachusetts Medical Society.

引用

页码：1194 / 1195

页数：2

共 5 条

[1]

miRNAs, cancer, and stem cell division [J].