DWARF 53 acts as a repressor of strigolactone signalling in rice

被引：682

作者：

Jiang, Liang ^{[1
,2
]}

Liu, Xue ^{[1
,2
]}

Xiong, Guosheng ^{[1
,2
]}

Liu, Huihui ^{[1
,2
]}

Chen, Fulu ^{[1
,2
]}

Wang, Lei ^{[1
,2
]}

Meng, Xiangbing ^{[1
,2
]}

Liu, Guifu ^{[1
,2
]}

Yu, Hong ^{[1
,2
]}

Yuan, Yundong ^{[1
,2
]}

Yi, Wei ^{[3
]}

Zhao, Lihua ^{[3
]}

Ma, Honglei ^{[3
]}

He, Yuanzheng ^{[4
]}

Wu, Zhongshan ^{[4
]}

Melcher, Karsten ^{[4
]}

Qian, Qian ^{[5
]}

Xu, H. Eric ^{[3
,4
]}

Wang, Yonghong ^{[1
,2
]}

Li, Jiayang ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Plant Genom, Beijing 100101, Peoples R China

[2] Chinese Acad Sci, Inst Genet & Dev Biol, Natl Ctr Plant Gene Res Beijing, Beijing 100101, Peoples R China

[3] Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, Ctr Struct & Funct Drug Targets,VARI SIMM Ctr, Shanghai 201203, Peoples R China

[4] Van Andel Res Inst, Lab Struct Sci, Grand Rapids, MI 49503 USA

[5] Chinese Acad Agr Sci, China Natl Rice Res Inst, State Key Lab Rice Biol, Hangzhou 310006, Zhejiang, Peoples R China

来源：

NATURE | 2013年 / 504卷 / 7480期

基金：

中国国家自然科学基金;

关键词：

ORYZA-SATIVA-L; CO-REPRESSOR; ARABIDOPSIS; TOPLESS; OUTGROWTH; KARRIKIN; ORTHOLOG; GENES; MAX1; LEAF;

D O I：

10.1038/nature12870

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Strigolactones (SLs) are a group of newly identified plant hormones that control plant shoot branching. SL signalling requires the hormone-dependent interaction of DWARF14 (D14), a probable candidate SL receptor, with DWARF3 (D3), an F-box component of the Skp-Cullin-F-box (SCF) E3 ubiquitin ligase complex. Here we report the characterization of a dominant SL-insensitive rice (Oryza sativa) mutant dwarf 53 (d53) and the cloning of D53, which encodes a substrate of the SCFD3 ubiquitination complex and functions as a repressor of SL signalling. Treatments with GR24, a synthetic SL analogue, cause D53 degradation via the proteasome in a manner that requires D14 and the SCFD3 ubiquitin ligase, whereas the dominant form of D53 is resistant to SL-mediated degradation. Moreover, D53 can interact with transcriptional co-repressors known as TOPLESS-RELATED PROTEINS. Our results suggest a model of SL signalling that involves SL-dependent degradation of the D53 repressor mediated by the D14-D3 complex.

引用

页码：401 / +

页数：17

共 50 条

[1] Plant sesquiterpenes induce hyphal branching in arbuscular mycorrhizal fungi [J].

Akiyama, K ;

Matsuzaki, K ;

Hayashi, H .

NATURE, 2005, 435 (7043) :824-827

[2] The Path from β-Carotene to Carlactone, a Strigolactone-Like Plant Hormone [J].

Alder, Adrian ;

Jamil, Muhammad ;

Marzorati, Mattia ;

Bruno, Mark ;

Vermathen, Martina ;

Bigler, Peter ;

Ghisla, Sandro ;

Bouwmeester, Harro ;

Beyer, Peter ;

Al-Babili, Salim .

SCIENCE, 2012, 335 (6074) :1348-1351

[3] DWARF10, an RMS1/MAX4/DAD1 ortholog, controls lateral bud outgrowth in rice [J].

Arite, Tomotsugu ;

Iwata, Hirotaka ;

Ohshima, Kenji ;

Maekawa, Masahiko ;

Nakajima, Masatoshi ;

Kojima, Mikiko ;

Sakakibara, Hitoshi ;

Kyozuka, Junko .

PLANT JOURNAL, 2007, 51 (06) :1019-1029

[4] d14, a Strigolactone-Insensitive Mutant of Rice, Shows an Accelerated Outgrowth of Tillers [J].

Arite, Tomotsugu ;

Umehara, Mikihisa ;

Ishikawa, Shinji ;

Hanada, Atsushi ;

Maekawa, Masahiko ;

Yamaguchi, Shinjiro ;

Kyozuka, Junko .

PLANT AND CELL PHYSIOLOGY, 2009, 50 (08) :1416-1424

[5] A novel system for gene silencing using siRNAs in rice leaf and stem-derived protoplasts [J].

Bart, Rebecca ;

Chern, Mawsheng ;

Park, Chang-Jin ;

Bartley, Laura ;

Ronald, Pamela C. .

PLANT METHODS, 2006, 2 (1)

[6] MAX1 encodes a cytochrome P450 family member that acts downstream of MAX3/4 to produce a carotenoid-derived branch-inhibiting hormone [J].

Booker, J ;

Sieberer, T ;

Wright, W ;

Williamson, L ;

Willett, B ;

Stirnberg, P ;

Turnbull, C ;

Srinivasan, M ;

Goddard, P ;

Leyser, O .

DEVELOPMENTAL CELL, 2005, 8 (03) :443-449

[7] MAX3/CCD7 is a carotenoid cleavage dioxygenase required for the synthesis of a novel plant signaling molecule [J].

Booker, J ;

Auldridge, M ;

Wills, S ;

McCarty, D ;

Klee, H ;

Leyser, O .

CURRENT BIOLOGY, 2004, 14 (14) :1232-1238

[8] The TOPLESS Interactome: A Framework for Gene Repression in Arabidopsis [J].

Causier, Barry ;

Ashworth, Mary ;

Guo, Wenjia ;

Davies, Brendan .

PLANT PHYSIOLOGY, 2012, 158 (01) :423-438

[9]

CHU CC, 1975, SCI SINICA, V18, P659

[10] GERMINATION OF WITCHWEED (STRIGA LUTEA LOUR) - ISOLATION AND PROPERTIES OF A POTENT STIMULANT [J].

COOK, CE ;

WHICHARD, LP ;

TURNER, B ;

WALL, ME .

SCIENCE, 1966, 154 (3753) :1189-&

← 1 2 3 4 5 →