Micro RNAs in animal development

被引：398

作者：

Plasterk, RHA ^{[1
]}

机构：

[1] Univ Utrecht, Hubrecht Lab, KNAW, NL-3584 CT Utrecht, Netherlands

来源：

CELL | 2006年 / 124卷 / 05期

关键词：

D O I：

10.1016/j.cell.2006.02.030

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Micro RNAs (miRNAs) are similar to 22 nucleotide single-stranded noncoding RNA molecules that bind to target messenger RNAs (mRNAs) and silence their expression. This Essay explores the importance of miRNAs in animal development and their possible roles in disease and evolution.

引用

页码：877 / 881

页数：5

共 22 条

[1] The let-7 microRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans
Abbott, AL
Alvarez-Saavedra, E
Miska, EA
Lau, NC
Bartel, DP
Horvitz, HR
Ambros, V
[J]. DEVELOPMENTAL CELL, 2005, 9 (03) : 403 - 414
[2] Sequence variants in SLITRK1 are associated with Tourette's syndrome
Abelson, JF
Kwan, KY
O'Roak, BJ
Baek, DY
Stillman, AA
Morgan, TM
Mathews, CA
Pauls, DA
Rasin, MR
Gunel, M
Davis, NR
Ercan-Sencicek, AG
Guez, DH
Spertus, JA
Leckman, JF
Dure, LS
Kurlan, R
Singer, HS
Gilbert, DL
Farhi, A
Louvi, A
Lifton, RP
Sestan, N
State, MW
[J]. SCIENCE, 2005, 310 (5746) : 317 - 320
[3] Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation
Bagga, S
Bracht, J
Hunter, S
Massirer, K
Holtz, J
Eachus, R
Pasquinelli, AE
[J]. CELL, 2005, 122 (04) : 553 - 563
[4] MicroRNAs: Genomics, biogenesis, mechanism, and function (Reprinted from Cell, vol 116, pg 281-297, 2004)
Bartel, David P.
[J]. CELL, 2007, 131 (04) : 11 - 29
[5] Identification of hundreds of conserved and nonconserved human microRNAs
Bentwich, I
Avniel, A
Karov, Y
Aharonov, R
Gilad, S
Barad, O
Barzilai, A
Einat, P
Einav, U
Meiri, E
Sharon, E
Spector, Y
Bentwich, Z
[J]. NATURE GENETICS, 2005, 37 (07) : 766 - 770
[6] Phylogenetic shadowing and computational identification of human microRNA genes
Berezikov, E
Guryev, V
van de Belt, J
Wienholds, E
Plasterk, RHA
Cuppen, E
[J]. CELL, 2005, 120 (01) : 21 - 24
[7] The widespread impact of mammalian microRNAs on mRNA repression and evolution
Farh, KKH
Grimson, A
Jan, C
Lewis, BP
Johnston, WK
Lim, LP
Burge, CB
Bartel, DP
[J]. SCIENCE, 2005, 310 (5755) : 1817 - 1821
[8] MicroRNAs regulate brain morphogenesis in zebrafish
Giraldez, AJ
Cinalli, RM
Glasner, ME
Enright, AJ
Thomson, JM
Baskerville, S
Hammond, SM
Bartel, DP
Schier, AF
[J]. SCIENCE, 2005, 308 (5723) : 833 - 838
[9] A microRNA polycistron as a potential human oncogene
He, L
Thomson, JM
Hemann, MT
Hernando-Monge, E
Mu, D
Goodson, S
Powers, S
Cordon-Cardo, C
Lowe, SW
Hannon, GJ
Hammond, SM
[J]. NATURE, 2005, 435 (7043) : 828 - 833
[10] The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development
Hornstein, E
Mansfield, JH
Yekta, S
Hu, JKH
Harfe, BD
McManus, MT
Baskerville, S
Bartel, DP
Tabin, CJ
[J]. NATURE, 2005, 438 (7068) : 671 - 674

← 1 2 3 →