Facile synthesis of enantiopure (-)-TAN1251A

被引：42

作者：

Mizutani, H ^{[1
]}

Takayama, J ^{[1
]}

Soeda, Y ^{[1
]}

Honda, T ^{[1
]}

机构：

[1] Hoshi Univ, Fac Pharmaceut Sci, Tokyo 1428501, Japan

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 13期

关键词：

D O I：

10.1016/S0040-4039(02)00296-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Formal total synthesis of enantiopure (-)-TAN125lA, a muscarinic M, receptor antagonist, was achieved via a spirocyclic carbon-nitrogen bond formation by the use of aromatic oxidation with bis(acetoxy)iodobenzene as a key step. (C) 2002 Elsevier Science Ltd. All rights reserved.

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页码：2411 / 2414

页数：4

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